PLOD3 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL2148885	0.53	4/20
SCHEMBL1924749	1.00	3/20
SCHEMBL1925385	1.00	3/20
SCHEMBL523476	0.67	3/20
SCHEMBL340946	0.66	3/20
SCHEMBL3108729	0.64	3/20
SCHEMBL1919299	0.60	3/20
SCHEMBL1062957	0.56	3/20
Phenanthroline (SCHEMBL3130843)	0.56	3/20
SCHEMBL2724408	0.55	3/20
SCHEMBL2851867	0.51	3/20
SCHEMBL341384	0.49	3/20
SCHEMBL1682774	0.49	3/20
SCHEMBL1682776	0.46	3/20
SCHEMBL2262230	0.46	3/20
SCHEMBL340456	0.45	3/20
SCHEMBL2647562	0.42	3/20
SCHEMBL200805	0.73	2/20
SCHEMBL313164	0.68	2/20
SCHEMBL2694778	0.65	2/20

Clinical trials — most relevant to PLOD3 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
PRP in ACLR to Prevent PTOA	PHASE3	RECRUITING
Trial of PXS-5505 Combined With First Line Atezolizumab Plus Bevacizumab For Treating Patients With Unresectable Hepatocellular Carcinoma	PHASE1/PHASE2	WITHDRAWN
Efficacy and Safety of Oltipraz in the Patients With Liver Fibrosis and Cirrhosis	PHASE2	COMPLETED
Doxycycline in Human Pulmonary Tuberculosis	PHASE2	COMPLETED
Fibroblast Specific Inhibition of LOXL2 and TGFbeta1 Signaling in Patients With Pulmonary Fibrosis.	EARLY_PHASE1	COMPLETED
Systemic Markers of Collagen Metabolism and Vitamin C in Smokers and Non-Smokers With Pelvic Organ Prolapse	nan	COMPLETED
Evaluation of Different Serum Cartilage Biomarkers in the Acute Response to Walking and Cycling in Healthy Male Subjects	nan	AVAILABLE
Pathogenesis of Compromised Bone Quality and Mechanics in Chronic Kidney Disease	nan	COMPLETED
Platelet Rich Plasma for Treatment of Facial Photoaging: A Double-blind, Randomized, Split-face Study	nan	UNKNOWN
The Effect of Vitamin C on Wound Healing In Mandibular Fracture Patients	nan	COMPLETED
Collagenase Chemonucleolysis vs Percutaneous Endoscopic Lumbar Discectomy (PELD) for Lumbar Disc Herniation	nan	UNKNOWN
CaREFREE Study (Calorie Restriction, Environment and Fitness: Reproductive Effects Evaluation Study)	nan	COMPLETED
Ventricular Matrix Remodeling: Correlates and Prognosis	nan	COMPLETED
Genetics of Ehlers-Danlos Syndrome	nan	COMPLETED
Serum COMP and MMP-3 in Knee Osteoarthritis	nan	NOT_YET_RECRUITING
Phenotype/Genotype Correlation in a Family With Early Onset Osteoarthritis	nan	COMPLETED
Expression of Fas Protein in Skin Biopsies of Participants With Scarring Alopecia	nan	COMPLETED
Evaluation of Horizontal Mandibular Ridge Augmentation Through Subperiosteal Tunneling by Using Bovine Sticky Bone (Radio-Histological Study)	nan	COMPLETED
Gene First Approach to Connective Tissue Disease	nan	COMPLETED
Serum Anti-PCOLCE as Novel Diagnostic Biomarker in Rheumatoid Arthritis With Emphasis on Seronegative Patients.	nan	NOT_YET_RECRUITING
The LD Lync Study - Natural History Study of Lipodystrophy Syndromes	nan	RECRUITING
Albumin Modifications as Early Biomarkers of Chronic Liver Diseases	nan	RECRUITING
Correlation Between Cytokines and Hepatic Histology in Patients Infected by HIV-1 and the Hepatitis-C Virus	nan	UNKNOWN
Circulating P3NP and Cardiovascular Events in Hemodialysis Patients	nan	COMPLETED
Linkage Study in Familial Pulmonary Fibrosis	nan	COMPLETED
Studies of Heritable Disorders of Connective Tissue	nan	COMPLETED
To Study the Effects of Host Genetic Factors on Liver Cirrhosis and Hepatocellular Carcinoma (HCC)	nan	UNKNOWN
Effects of a Dietary Supplement on Collagen Production and Evaluation of Its Regenerative and Anti-Ageing Propertiess	nan	COMPLETED
Assessment of Anorectal Function in Patients With Inflammatory Bowel Disease	nan	RECRUITING
Noninvasive Tests to Predict the Presence of Esophageal Varices in Patients With Liver Cirrhosis	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a PLOD3 binder may also engage these)

Protein	Name	Similarity
Q5R6K5	—	1.000	Q5R6K5 →
Q5U367	—	1.000	Q5U367 →
Q9R0E1	—	1.000	Q9R0E1 →
O97583	—	0.982	O97583 →
P52849	—	0.977	P52849 →
P52850	—	0.976	P52850 →
Q5T4B2	—	0.976	Q5T4B2 →
COLGALT1	Procollagen galactosyltransferase 1	0.974	landscape →
Q8K297	—	0.971	Q8K297 →
A7MB73	—	0.971	A7MB73 →
Q5R9N3	—	0.971	Q5R9N3 →
Q812F8	—	0.971	Q812F8 →
O77588	—	0.968	O77588 →
Q9UQ53	—	0.968	Q9UQ53 →
A5PK45	—	0.968	A5PK45 →
O09010	—	0.967	O09010 →
G5E897	—	0.967	G5E897 →
Q6EV70	—	0.966	Q6EV70 →
Q5U4X8	—	0.965	Q5U4X8 →
P83337	—	0.964	P83337 →
Q9H488	—	0.964	Q9H488 →
Q566E5	—	0.962	Q566E5 →
Q66PG4	—	0.962	Q66PG4 →
Q8CFC4	—	0.962	Q8CFC4 →
Q91ZW2	—	0.962	Q91ZW2 →
O09009	—	0.962	O09009 →
O12971	—	0.962	O12971 →
Q6KFX9	—	0.962	Q6KFX9 →
Q5IGR7	—	0.962	Q5IGR7 →
Q7Z4H8	—	0.961	Q7Z4H8 →