SCHEMBL11940286

SCHEMBL11940286

CC(C)(C)C(C#N)=C(C#N)C#N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20034052 0.83 TDP1 (0.33)
SCHEMBL16167910 0.83 TDP1 (0.33)
SCHEMBL1108123 0.73 TDP1 (0.33)
SCHEMBL16307982 0.73 TDP1 (0.33)
SCHEMBL9901551 0.69 TDP1 (0.35)
SCHEMBL444510 0.69 TDP1 (0.35)
SCHEMBL9296259 0.69 ALDH1A1 (0.32)
SCHEMBL9013075 0.67 ALDH1A1 (0.30)
SCHEMBL444507 0.67 KMT2A (0.36)
SCHEMBL11934055 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11236188-B2 Electro-optic polymer NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGY (JP) 2022-02-01 US disclosed
US-10754064-B2 Second-order nonlinear optical compound and nonlinear optical element comprising the same NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGY (JP) 2020-08-25 US disclosed
US-20190225728-A1 ELECTRO-OPTIC POLYMER NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGY (JP) 2019-07-25 US disclosed
US-20180224577-A1 SECOND-ORDER NONLINEAR OPTICAL COMPOUND AND NONLINEAR OPTICAL ELEMENT COMPRISING THE SAME NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGY (JP) 2018-08-09 US disclosed
US-9977150-B2 Second-order nonlinear optical compound and nonlinear optical element comprising the same NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGY (JP) 2018-05-22 US disclosed
US-8772048-B2 Fluorogenic compounds converted to fluorophores by photochemical or chemical means and their use in biological systems KENT STATE UNIVERSITY (US) 2014-07-08 US disclosed
US-20120190098-A1 FLUOROGENIC COMPOUNDS CONVERTED TO FLUOROPHORES BY PHOTOCHEMICAL OR CHEMICAL MEANS AND THEIR USE IN BIOLOGICAL SYSTEMS LELAND STANFORD JUNIOR UNIVERSITY (US) 2012-07-26 US disclosed
US-20120172599-A1 SECOND-ORDER NONLINEAR OPTICAL COMPOUND AND NONLINEAR OPTICAL ELEMENT COMPRISING THE SAME SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) 2012-07-05 US disclosed
US-20090087376-A1 Heterocyclic Dye Compounds For In Vivo Imaging And Diagnosis Of Alzheimer's Disease THE GENERAL HOSPITAL CORPORATION (US) 2009-04-02 US disclosed
US-7261953-B2 Multilayer ; pair of electrode with organic thiophene compound inbetween FUJIFILM CORPORATION (JP) 2007-08-28 US disclosed