Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4624875 | 0.69 | ALDH1A1 (0.36) | MAPTALDH1A1 | |
| SCHEMBL6035320 | 0.69 | ALDH1A1 (0.36) | MAPTALDH1A1 | |
| SCHEMBL456373 | 0.69 | ALDH1A1 (0.36) | KMT2AMAPTKDM4EMEN1LMNA | |
| SCHEMBL442469 | 0.69 | ALDH1A1 (0.36) | KMT2AMAPTKDM4EMEN1LMNA | |
| SCHEMBL456372 | 0.69 | ALDH1A1 (0.36) | KMT2AMAPTKDM4EMEN1LMNA | |
| SCHEMBL6050622 | 0.67 | KDM4E (0.33) | KMT2AMAPTKDM4EMEN1LMNA | |
| SCHEMBL9901551 | 0.67 | TDP1 (0.35) | — | |
| SCHEMBL444510 | 0.67 | TDP1 (0.35) | KDM4EALDH1A1 | |
| SCHEMBL11940286 | 0.67 | — | — | |
| SCHEMBL10644863 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8470739-B2 | Isothiazolyloxyphenylamidines and their use as fungicides | BAYER CROPSCIENE AG (DE) | 2013-06-25 | — | — | US | disclosed |
| US-8470739-B2 | Isothiazolyloxyphenylamidines and their use as fungicides | BAYER CROPSCIENE AG (DE) | 2013-06-25 | — | — | US | disclosed |
| US-8470739-B2 | Isothiazolyloxyphenylamidines and their use as fungicides | BAYER CROPSCIENE AG (DE) | 2013-06-25 | — | — | US | disclosed |
| CN-102388027-A | Isothiazolyloxyphenylamidines and their use as fungicides | BAYER CROPSCIENCE AG | 2012-03-21 | — | — | CN | disclosed |
| US-8138211-B2 | Isothiazolyloxyphenylamidines and their use as fungicides | BAYER CROPSCIENCE AG (DE) | 2012-03-20 | — | — | US | disclosed |
| US-8138211-B2 | Isothiazolyloxyphenylamidines and their use as fungicides | BAYER CROPSCIENCE AG (DE) | 2012-03-20 | — | — | US | disclosed |
| US-8138211-B2 | Isothiazolyloxyphenylamidines and their use as fungicides | BAYER CROPSCIENCE AG (DE) | 2012-03-20 | — | — | US | disclosed |
| US-20120065061-A1 | ISOTHIAZOLYLOXYPHENYLAMIDINES AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2012-03-15 | — | — | US | disclosed |
| US-20120065061-A1 | ISOTHIAZOLYLOXYPHENYLAMIDINES AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2012-03-15 | — | — | US | disclosed |
| US-20120065061-A1 | ISOTHIAZOLYLOXYPHENYLAMIDINES AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2012-03-15 | — | — | US | disclosed |
| EP-2391612-A1 | Isothiazolyloxyphenyl amidines and use thereof as fungicides | Bayer CropScience AG (DE) | 2011-12-07 | — | — | EP | disclosed |
| US-20110130282-A1 | Isothiazolyloxyphenylamidines and their use as fungicides | BAYER CROPSCIENCE AG (DE) | 2011-06-02 | — | — | US | disclosed |
| US-20110130282-A1 | Isothiazolyloxyphenylamidines and their use as fungicides | BAYER CROPSCIENCE AG (DE) | 2011-06-02 | — | — | US | disclosed |
| US-20110130282-A1 | Isothiazolyloxyphenylamidines and their use as fungicides | BAYER CROPSCIENCE AG (DE) | 2011-06-02 | — | — | US | disclosed |
| EP-2223917-A1 | Isothiazolyloxyphenylamidines and their use as fungicides | Bayer CropScience AG (DE) | 2010-09-01 | — | — | EP | disclosed |
| EP-2223917-A1 | Isothiazolyloxyphenylamidines and their use as fungicides | Bayer CropScience AG (DE) | 2010-09-01 | — | — | EP | disclosed |
| WO-2010086118-A1 | ISOTHIAZOLYLOXYPHENYL AMIDINES AND USE THEREOF AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2010-08-05 | — | — | WO | disclosed |
| WO-2010086118-A1 | ISOTHIAZOLYLOXYPHENYL AMIDINES AND USE THEREOF AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2010-08-05 | — | — | WO | disclosed |
| EP-1344774-B1 | Synthesizing methods of dicyanomethylidene compound and heterocyclic compound | FUJI PHOTO FILM CO LTD (JP) | 2005-12-07 | — | — | EP | disclosed |
| EP-1344774-A1 | Synthesizing methods of dicyanomethylidene compound and heterocyclic compound | FUJI PHOTO FILM CO., LTD. (JP) | 2003-09-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065061-A1 | ISOTHIAZOLYLOXYPHENYLAMIDINES AND THEIR USE AS FUNGICIDES | DDT, CYP3A5, INMT | KMT2A 2601/4885MAPT 3061/4885KDM4E 2299/4885 |
| US-20110130282-A1 | Isothiazolyloxyphenylamidines and their use as fungicides | DDT, CYP3A5, INMT | KMT2A 2601/4885MAPT 3061/4885KDM4E 2299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.