Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 5/20 | 0.55 |
| ▸ | CCR1 | P32246 | 3/20 | 0.55 |
| ▸ | CCR5 | P51681 | 3/20 | 0.55 |
| ▸ | CCR8 | P51685 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | ALPL | P05186 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | ALPI | P09923 | 1/20 | 0.55 |
| ▸ | ALPG | P10696 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.52 |
| ▸ | METAP1 | P53582 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18210595 | 0.81 | AXL (0.44) | KDM4EL3MBTL1SMN1; SMN2TDP1MAPK1 | |
| SCHEMBL916878 | 0.76 | CCNT1 (0.48) | MAPK1 | |
| SCHEMBL18210602 | 0.76 | MAPK1 (0.40) | MAPK1METAP2AXLNUDT1 | |
| SCHEMBL144673 | 0.75 | CYP1A2 (0.53) | KDM4EL3MBTL1SMN1; SMN2MAPK1CYP1A2 | |
| SCHEMBL20595283 | 0.73 | BTK (0.50) | KDM4ELMNACCR1CCR5CCR8 | |
| Terpyridine SCHEMBL57442 | 0.73 | KDM4E (1.00) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL7964803 | 0.73 | KDM4E (1.00) | KDM4ELMNACCR1CCR5CCR8 | |
| Terpyridine SCHEMBL29357603 | 0.73 | KDM4E (1.00) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL30172832 | 0.73 | KDM4E (1.00) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL3711450 | 0.72 | KDM4E (1.00) | KDM4ELMNACCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12448362-B2 | Fluorine-containing pyrimidine compound and fluorine-containing pyrimidinone compound | UNIMATEC CO., LTD. (JP) | 2025-10-21 | — | — | US | disclosed |
| US-20250223274-A1 | FLUORINE-CONTAINING PYRIMIDINE COMPOUND AND FLUORINE-CONTAINING PYRIMIDINONE COMPOUND | UNIMATEC CO., LTD. (JP) | 2025-07-10 | — | — | US | disclosed |
| CN-119504704-A | Fluoropyrimidine compounds fluorine-containing pyrimidinone compound | 优迈特株式会社 | 2025-02-25 | — | — | CN | disclosed |
| CN-115551840-B | Fluoropyrimidine compounds fluorine-containing pyrimidinone compound | 优迈特株式会社 | 2024-12-03 | — | — | CN | disclosed |
| EP-4155299-A1 | FLUOROPYRIMIDINE COMPOUND AND FLUOROPYRIMIDINONE COMPOUND | Unimatec Co., Ltd. (JP) | 2023-03-29 | — | — | EP | disclosed |
| CN-115551840-A | Fluorine-containing pyrimidine compound and fluorine-containing pyrimidinone compound | 优迈特株式会社 | 2022-12-30 | — | — | CN | disclosed |
| CN-112771042-A | Nalidinone and pyridylpyrimidinone compounds as protein kinase inhibitors | 重庆复创医药研究有限公司 | 2021-05-07 | — | — | CN | disclosed |
| CN-112771042-A | Nalidinone and pyridylpyrimidinone compounds as protein kinase inhibitors | 重庆复创医药研究有限公司 | 2021-05-07 | — | — | CN | disclosed |
| EP-3291817-B1 | HETEROARYL-PYRIMIDINONE COMPOUNDS AS PDE2 INHIBITORS | MERCK SHARP & DOHME (US) | 2019-10-02 | — | — | EP | disclosed |
| US-10195201-B2 | Heteroaryl-pyrimidinone compounds as PDE2 inhibitors | MERCK SHARP & DOHME CORP. (US) | 2019-02-05 | — | — | US | disclosed |
| US-20040110777-A1 | Quinazolinones and pyridinylpyrimidinones for controlling invertebrate pests | E. I. DU PONT DE NEMOURS AND COMPANY | 2004-06-10 | — | — | US | disclosed |
| WO-2003101442-A1 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-12-11 | — | — | WO | disclosed |
| EP-1341772-A2 | QUINAZOLINONES AND PYRIDINYLPYRIMIDINONES FOR CONTROLLING INVERTEBRATE PESTS | E. I. du Pont de Nemours and Company (US) | 2003-09-10 | — | — | EP | disclosed |
| EP-0708090-B1 | Intermediates useful for the synthesis of pesticides | AVENTIS CROPSCIENCE SA (FR) | 2002-12-04 | — | — | EP | disclosed |
| WO-2002048115-A2 | QUINAZOLINONES AND PYRIDINOPYRIMIDINONES FOR CONTROLLING INVERTEBRATE PESTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-06-20 | — | — | WO | disclosed |
| US-6271392-B1 | Intermediates useful for the synthesis of 1-arylpyrrole pesticides | RHONE-POULENC INC. | 2001-08-07 | — | — | US | disclosed |
| EP-0708090-A1 | Intermediates useful for the synthesis of pesticides | RHONE-POULENC AGROCHIMIE (FR) | 1996-04-24 | — | — | EP | disclosed |
| US-4990512-A | Insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-02-05 | — | — | US | disclosed |
| US-4990512-A | Insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-02-05 | — | — | US | disclosed |
| EP-0357201-A2 | Pyridyl pyrimidinone derivatives with an insecticidal activity | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-03-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250223274-A1 | FLUORINE-CONTAINING PYRIMIDINE COMPOUND AND FLUORINE-CONTAINING PYRIMIDINONE COMPOUND | CNOT1, FXR1, NAT1 | KDM4E 4557/4885LMNA 2193/4885CCR1 319/4885 |
| US-20040110777-A1 | Quinazolinones and pyridinylpyrimidinones for controlling invertebrate pests | SYNJ1, SBK3, KCNK4 | KDM4E 858/4885LMNA 1960/4885CCR1 1911/4885 |
| US-10195201-B2 | Heteroaryl-pyrimidinone compounds as PDE2 inhibitors | PDE2A, PDE12, PDE7B | KDM4E 2517/4885LMNA 4612/4885CCR1 3806/4885 |
| US-12448362-B2 | Fluorine-containing pyrimidine compound and fluorine-containing pyrimidinone compound | CNOT1, FXR1, NAT1 | KDM4E 4557/4885LMNA 2193/4885CCR1 319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.