Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.36 |
| ▸ | MARS1 | P56192 | 2/20 | 0.35 |
| ▸ | HPD | P32754 | 1/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.35 |
| ▸ | EDNRB | P24530 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12119099 | 0.93 | HSD17B1 (0.40) | PTGS2MAPTHSD17B1MARS1SRD5A2 | |
| SCHEMBL11940724 | 0.90 | BRD4 (0.37) | MAPTHSD17B1HPDHPGDKDM4E | |
| SCHEMBL11940721 | 0.89 | HPD (0.40) | PTGS2MAPTHSD17B1HPDHPGD | |
| SCHEMBL11940722 | 0.88 | MAPT (0.36) | MAPTMEN1THRBRECQLKMT2A | |
| SCHEMBL11940679 | 0.88 | HSD17B1 (0.39) | MAPTMEN1THRBRECQLKMT2A | |
| SCHEMBL11940730 | 0.86 | AHR (0.39) | PTGS2MAPTMEN1THRBRECQL | |
| SCHEMBL11940726 | 0.84 | POLB (0.42) | PTGS2MAPTTHRBHSD17B1AHR | |
| SCHEMBL11940728 | 0.84 | HSD17B1 (0.34) | PTGS2MAPTMEN1THRBRECQL | |
| SCHEMBL11940719 | 0.83 | HSD17B1 (0.34) | PTGS2MAPTMEN1THRBRECQL | |
| SCHEMBL11940727 | 0.83 | MAPT (0.37) | PTGS2MAPTMEN1THRBRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8741806-B2 | Herbicides | SYNGENTA LIMITED (GB) | 2014-06-03 | — | — | US | disclosed |
| US-8741806-B2 | Herbicides | SYNGENTA LIMITED (GB) | 2014-06-03 | — | — | US | disclosed |
| US-20120190545-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120190545-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-07-26 | — | — | US | disclosed |
| WO-2011006543-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2011-01-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120190545-A1 | NOVEL HERBICIDES | DDT, CYP1B1, CYP1A1 | PTGS2 3383/4885MAPT 3984/4885MEN1 4244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.