Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH2 | P05091 | 5/20 | 0.65 |
| ▸ | NPC1 | O15118 | 5/20 | 0.61 |
| ▸ | RAB9A | P51151 | 5/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 4/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.61 |
| ▸ | RELA | Q04206 | 3/20 | 0.61 |
| ▸ | TP53 | P04637 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | ACHE | P22303 | 3/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | MAOA | P21397 | 3/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2751806 | 0.96 | ALDH2 (0.62) | ALDH2NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL26145338 | 0.93 | NPC1 (0.71) | ALDH2NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL26848473 | 0.90 | ALDH2 (0.63) | ALDH2NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL2750320 | 0.89 | ALDH2 (0.61) | ALDH2NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL7565641 | 0.87 | MEN1 (0.63) | ALDH2NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL30380086 | 0.85 | KDM4E (0.61) | ALDH2NPC1RAB9ASMN1; SMN2MEN1 | |
| 7-Acetoxy-4',5-Dihydroxygenistein SCHEMBL10001910 | 0.83 | ALDH2 (0.75) | ALDH2NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL13911077 | 0.83 | ALDH2 (0.65) | ALDH2NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL16473745 | 0.83 | ACHE (0.77) | ALDH2NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL26145321 | 0.82 | KDM4E (0.69) | ALDH2NPC1RAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140107051-A1 | ISOFLAVONES FOR TREATING MUCOPOLYSACCHARIDOSES | INSTYTUT FARMACEUTYCZNY (PL) | 2014-04-17 | — | — | US | disclosed |
| US-8623910-B2 | Isoflavones for treating mucopolysaccharidoses | INSTYTUT FARMACEUTYCZNY (PL) | 2014-01-07 | — | — | US | disclosed |
| US-20120190642-A1 | ISOFLAVONES FOR TREATING MUCOPOLYSACCHARIDOSES | INSTYTUT FARMACEUTYCZNY (PL) | 2012-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140107051-A1 | ISOFLAVONES FOR TREATING MUCOPOLYSACCHARIDOSES | GAA, MAN2B1, IDUA | ALDH2 3383/4885NPC1 180/4885RAB9A 1624/4885 |
| US-20120190642-A1 | ISOFLAVONES FOR TREATING MUCOPOLYSACCHARIDOSES | GAA, MAN2B1, IDUA | ALDH2 3553/4885NPC1 171/4885RAB9A 1706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.