Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.71 |
| ▸ | RAB9A | P51151 | 7/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.71 |
| ▸ | MEN1 | O00255 | 5/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.71 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.71 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.71 |
| ▸ | RELA | Q04206 | 3/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | TP53 | P04637 | 5/20 | 0.66 |
| ▸ | MAPT | P10636 | 5/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | HPGD | P15428 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11940752 | 0.93 | ALDH2 (0.65) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL26145321 | 0.90 | KDM4E (0.69) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL2751806 | 0.89 | ALDH2 (0.62) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7565641 | 0.86 | MEN1 (0.63) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL26145336 | 0.85 | NPC1 (0.67) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL30380086 | 0.85 | KDM4E (0.61) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL26145337 | 0.84 | RAB9A (0.82) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| 4',7-Dimethoxy-5-Hydroxygenistein SCHEMBL572108 | 0.84 | RAB9A (1.00) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL26848473 | 0.83 | ALDH2 (0.63) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL2750320 | 0.82 | ALDH2 (0.61) | NPC1RAB9ASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230149344-A1 | BIOCHANIN A DERIVATIVES FOR TREATMENT OF BEST1-RELATED RETINOPATHIES | UNIVERSITÄT REGENSBURG (AT) | 2023-05-18 | — | — | US | disclosed |
| US-20230149344-A1 | BIOCHANIN A DERIVATIVES FOR TREATMENT OF BEST1-RELATED RETINOPATHIES | UNIVERSITÄT REGENSBURG (AT) | 2023-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230149344-A1 | BIOCHANIN A DERIVATIVES FOR TREATMENT OF BEST1-RELATED RETINOPATHIES | SORBS1, SLC5A6, SLC20A1 | NPC1 1509/4885RAB9A 1919/4885SMN1; SMN2 252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.