Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 3/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10302844 | 0.89 | ADRA2A (0.49) | ADRA2AADRA2BADRA2CADRB2ADRA1A | |
| SCHEMBL14510529 | 0.79 | CES2 (0.42) | ADRA2AADRA2BADRA2CADRB2ADRA1A | |
| SCHEMBL11943453 | 0.78 | PDE5A (0.43) | ADRA2AADRA2BADRA2CADRA1APDE5A | |
| SCHEMBL10303345 | 0.76 | ADRA2A (0.41) | ADRA2AADRA2BADRA2CADRB2ADRA1A | |
| SCHEMBL12223952 | 0.76 | ADRA2A (0.41) | ADRA2AADRA2BADRA2CADRB2ADRA1A | |
| SCHEMBL8746393 | 0.76 | CES2 (0.42) | ADRA2AADRA2BADRA2CADRB1ADRB3 | |
| SCHEMBL7523840 | 0.75 | PPARG (0.42) | ADRA2AADRA2BADRA2CADRB1ADRB3 | |
| SCHEMBL8746416 | 0.75 | PPARG (0.42) | ADRA2AADRA2BADRA2CADRB1ADRB3 | |
| SCHEMBL4290441 | 0.75 | PPARG (0.42) | ADRA2AADRA2BADRA2CADRB1ADRB3 | |
| SCHEMBL4825249 | 0.75 | PPARG (0.42) | ADRA2AADRA2BADRA2CADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2479162-A1 | LIQUID CRYSTALLINE COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT | JNC Corporation (JP) | 2012-07-25 | — | — | EP | disclosed |