Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.49 |
| ▸ | PRCP | P42785 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 4/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11948859 | 0.90 | PRCP (0.58) | HDAC1HDAC8HDAC2HDAC3NCOR2 | |
| SCHEMBL4399615 | 0.87 | HDAC3 (0.51) | HDAC1HDAC8HDAC2HDAC3NCOR2 | |
| SCHEMBL11948851 | 0.86 | PRCP (0.46) | HDAC1HDAC8HDAC2HDAC3NCOR2 | |
| SCHEMBL11948854 | 0.84 | PRCP (0.55) | HDAC1HDAC8HDAC2HDAC3NCOR2 | |
| SCHEMBL11948850 | 0.78 | PRCP (0.42) | HDAC1HDAC8HDAC2HDAC3NCOR2 | |
| SCHEMBL4402003 | 0.77 | PRCP (0.56) | HDAC1HDAC8HDAC2HDAC3NCOR2 | |
| SCHEMBL4391630 | 0.73 | HDAC8 (0.46) | HDAC1HDAC8HDAC2HDAC3NCOR2 | |
| SCHEMBL4388627 | 0.70 | PRCP (0.54) | HDAC1HDAC8HDAC2HDAC3NCOR2 | |
| SCHEMBL4391667 | 0.68 | PRCP (0.51) | HDAC1HDAC8HDAC2HDAC3NCOR2 | |
| SCHEMBL14417385 | 0.68 | PRCP (0.70) | HDAC1HDAC8HDAC2HDAC3NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8232399-B2 | Chiral ligands, their preparation and uses thereof in asymmetric reactions | Li, Chao-Jun (CA) | 2012-07-31 | — | — | US | disclosed |