Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 2/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | DRD1 | P21728 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4388627 | 0.85 | PRCP (0.54) | PRCPHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL11948849 | 0.84 | HDAC1 (0.49) | PRCPHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL4391667 | 0.83 | PRCP (0.51) | PRCPHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL11948850 | 0.83 | PRCP (0.42) | PRCPHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL11948859 | 0.83 | PRCP (0.58) | PRCPHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL11948851 | 0.81 | PRCP (0.46) | PRCPHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL4544071 | 0.80 | PRCP (0.51) | PRCPHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL11956302 | 0.80 | PRCP (0.51) | PRCPHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL4396690 | 0.79 | PRCP (0.49) | PRCPHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL4390219 | 0.75 | DRD2 (0.48) | PRCPHDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8232399-B2 | Chiral ligands, their preparation and uses thereof in asymmetric reactions | Li, Chao-Jun (CA) | 2012-07-31 | — | — | US | disclosed |