Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | PRCP | P42785 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11948851 | 0.87 | PRCP (0.46) | HDAC8HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL4402003 | 0.86 | PRCP (0.56) | HDAC8HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL4399615 | 0.84 | HDAC3 (0.51) | HDAC8HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL4388627 | 0.79 | PRCP (0.54) | HDAC8HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL14371835 | 0.77 | KDM4E (0.51) | KDM4EALDH1A1GAAMAPT | |
| SCHEMBL2793914 | 0.76 | PRCP (0.70) | HDAC8HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL11948852 | 0.75 | MTNR1B (0.46) | HDAC8HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL11948859 | 0.75 | PRCP (0.58) | HDAC8HDAC3HDAC1HDAC2NCOR2 | |
| Bromide SCHEMBL27345751 | 0.74 | PRCP (0.68) | HDAC8HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL11948849 | 0.73 | HDAC1 (0.49) | HDAC8HDAC3HDAC1HDAC2NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8232399-B2 | Chiral ligands, their preparation and uses thereof in asymmetric reactions | Li, Chao-Jun (CA) | 2012-07-31 | — | — | US | disclosed |
| US-20090306390-A1 | CHIRAL LIGANDS, THEIR PREPARATION AND USES THEREOF IN ASYMMETRIC REACTIONS | CHAO-JUN LI (CA) | 2009-12-10 | — | — | US | disclosed |
| WO-2007098608-A1 | CHIRAL LIGANDS, THEIR PREPARATION AND USES THEREOF IN ASSYMETRIC REACTIONS | LI CHAO-JUN (CA) | 2007-09-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306390-A1 | CHIRAL LIGANDS, THEIR PREPARATION AND USES THEREOF IN ASYMMETRIC REACTIONS | OR10J3, C1R, C3AR1 | HDAC8 3678/4885HDAC3 1862/4885HDAC1 2637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.