Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.39 |
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11949961 | 0.81 | ALDH1A1 (0.37) | CYP1A2ALDH1A1RAB9ATP53LMNA | |
| SCHEMBL21826830 | 0.73 | CYP1A2 (0.44) | CYP1A2CYP2D6ALDH1A1RAB9ACTSK | |
| SCHEMBL21885839 | 0.73 | CYP1A2 (0.44) | CYP1A2CYP2D6ALDH1A1RAB9ACTSK | |
| SCHEMBL21826865 | 0.71 | CYP1A2 (0.48) | CYP1A2CYP2D6ALDH1A1RAB9AHSD17B10 | |
| SCHEMBL21826862 | 0.71 | CYP1A2 (0.48) | CYP1A2CYP2D6ALDH1A1RAB9AHSD17B10 | |
| SCHEMBL11410916 | 0.70 | ALDH1A1 (0.37) | ALDH1A1HSD17B10LMNAKDM4EMAPK1 | |
| SCHEMBL11948976 | 0.70 | ALDH1A1 (0.37) | ALDH1A1HSD17B10LMNAKDM4EMAPK1 | |
| SCHEMBL11323483 | 0.70 | ALDH1A1 (0.37) | ALDH1A1HSD17B10LMNAKDM4EMAPK1 | |
| SCHEMBL14534032 | 0.70 | CYP1A2 (0.31) | CYP1A2CYP2D6SMN1; SMN2CYP2C19 | |
| SCHEMBL11319709 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2665722-B1 | PROCESS FOR THE PREPARATION OF DIOL SULFONES | DSM SINOCHEM PHARM NL BV (NL) | 2016-08-17 | — | — | EP | disclosed |
| US-9150562-B2 | Process for the preparation of diol sulfones | DSM SINOCHEM PHARMACEUTICALS NETHERLANDS B.V. (NL) | 2015-10-06 | — | — | US | disclosed |
| US-9150562-B2 | Process for the preparation of diol sulfones | DSM SINOCHEM PHARMACEUTICALS NETHERLANDS B.V. (NL) | 2015-10-06 | — | — | US | disclosed |
| EP-2665721-B1 | METHYLTETRAZOLE SULFIDES AND SULFONES | DSM SINOCHEM PHARM NL BV (NL) | 2015-07-08 | — | — | EP | disclosed |
| US-8865900-B2 | Methyltetrazole sulfides and sulfones | DSM SINOCHEM PHARMACEUTICALS NETHERLANDS B.V. (NL) | 2014-10-21 | — | — | US | disclosed |
| US-8865900-B2 | Methyltetrazole sulfides and sulfones | DSM SINOCHEM PHARMACEUTICALS NETHERLANDS B.V. (NL) | 2014-10-21 | — | — | US | disclosed |
| US-20130303779-A1 | PROCESS FOR THE PREPARATION OF DIOL SULFONES | DSM SINOCHEM PHARMACEUTICALS NETHERLANDS B.V. (NL) | 2013-11-14 | — | — | US | disclosed |
| US-20130303779-A1 | PROCESS FOR THE PREPARATION OF DIOL SULFONES | DSM SINOCHEM PHARMACEUTICALS NETHERLANDS B.V. (NL) | 2013-11-14 | — | — | US | disclosed |
| US-20130296563-A1 | METHYLTETRAZOLE SULFIDES AND SULFONES | DSM SINOCHEM PHARMACEUTICALS NETHERLANDS B.V. (NL) | 2013-11-07 | — | — | US | disclosed |
| US-20130296563-A1 | METHYLTETRAZOLE SULFIDES AND SULFONES | DSM SINOCHEM PHARMACEUTICALS NETHERLANDS B.V. (NL) | 2013-11-07 | — | — | US | disclosed |
| WO-2012098048-A1 | PROCESS FOR THE PREPARATION OF DIOL SULFONES | DSM SINOCHEM PHARMACEUTICALS NETHERLANDS B.V. (NL) | 2012-07-26 | — | — | WO | disclosed |
| WO-2012098050-A1 | METHYLTETRAZOLE SULFIDES AND SULFONES | DSM SINOCHEM PHARMACEUTICALS NETHERLANDS B.V. (NL) | 2012-07-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130303779-A1 | PROCESS FOR THE PREPARATION OF DIOL SULFONES | STS, DHCR7, TST | CYP1A2 85/4885CYP2D6 60/4885ALDH1A1 927/4885 |
| US-20130296563-A1 | METHYLTETRAZOLE SULFIDES AND SULFONES | TST, STS, TPMT | CYP1A2 119/4885CYP2D6 115/4885ALDH1A1 1545/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.