SCHEMBL11949443

SCHEMBL11949443

COC(=O)c1ccccc1C(=O)Oc1ccc(C(C)(C)c2ccc(OC(=O)Oc3ccc(C(C)(C)c4ccc(C)cc4)cc3)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 3/20 0.54
▸ NPSR1 Q6W5P4 2/20 0.54
▸ PTK2B Q14289 1/20 0.49
▸ RXFP1 Q9HBX9 1/20 0.49
▸ KMT2A Q03164 3/20 0.48
▸ MEN1 O00255 1/20 0.48
▸ ALDH1A1 P00352 5/20 0.46
▸ ELANE P08246 1/20 0.45
▸ PRTN3 P24158 1/20 0.45
▸ CYP1A2 P05177 2/20 0.44
▸ CYP3A4 P08684 1/20 0.44
▸ CYP2C9 P11712 1/20 0.44
▸ CYP2C19 P33261 1/20 0.44
▸ TDP1 Q9NUW8 1/20 0.43
▸ L3MBTL1 Q9Y468 1/20 0.43
▸ MAOA P21397 1/20 0.42
▸ MAOB P27338 1/20 0.42
▸ HPGD P15428 4/20 0.42
▸ HSD17B10 Q99714 2/20 0.42
▸ XBP1 P17861 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12289275 0.96 MAPT (0.58) MAPTNPSR1PTK2BRXFP1KMT2A
SCHEMBL12300579 0.86 MAPT (0.59) MAPTNPSR1KMT2AMEN1ALDH1A1
SCHEMBL13865007 0.85 MAPT (0.56) MAPTNPSR1PTK2BRXFP1KMT2A
SCHEMBL13985890 0.85 MAPT (0.55) MAPTNPSR1PTK2BRXFP1KMT2A
SCHEMBL26030951 0.84 TDP1 (0.56) MAPTKMT2AMEN1ALDH1A1TDP1
SCHEMBL10027744 0.83 TDP1 (0.49) MAPTNPSR1KMT2AMEN1ALDH1A1
SCHEMBL16488968 0.83 TDP1 (0.49) MAPTNPSR1KMT2AMEN1ALDH1A1
SCHEMBL15827154 0.83 LMNA (0.53) MAPTNPSR1KMT2AMEN1ALDH1A1
SCHEMBL5706122 0.82 MAPT (0.54) MAPTNPSR1KMT2AMEN1ALDH1A1
SCHEMBL410353 0.81 LMNA (0.48) MAPTNPSR1KMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8859667-B2 Carbon nanotube filled polycarbonate anti-curl back coating with improved electrical and mechanical properties XEROX CORPORATION (US) 2014-10-14 — — US disclosed
US-8263301-B2 Low friction electrostatographic imaging member XEROX CORPORATION (US) 2012-09-11 — — US disclosed
US-8232032-B2 Low friction electrostatographic imaging member XEROX CORPORATION (US) 2012-07-31 — — US disclosed
US-8084173-B2 Low friction electrostatographic imaging member XEROX CORPORATION (US) 2011-12-27 — — US disclosed
US-20110255904-A1 LOW FRICTION ELECTROSTATOGRAPHIC IMAGING MEMBER XEROX CORPORATION (US) 2011-10-20 — — US disclosed
US-8026028-B2 Low friction electrostatographic imaging member XEROX CORPORATION (US) 2011-09-27 — — US disclosed
US-8021812-B2 Low friction electrostatographic imaging member XEROX CORPORATION (US) 2011-09-20 — — US disclosed
US-8007970-B2 Low friction electrostatographic imaging member XEROX CORPORATION (US) 2011-08-30 — — US disclosed
US-7998646-B2 Low friction electrostatographic imaging member XEROX CORPORATION (US) 2011-08-16 — — US disclosed
US-20110176831-A1 LOW FRICTION ELECTROSTATOGRAPHIC IMAGING MEMBER XEROX CORPORATION (US) 2011-07-21 — — US disclosed
US-20090325094-A1 IMAGING MEMBER XEROX CORPORATION (US) 2009-12-31 — — US disclosed
US-7618757-B2 Imaging member having first and second charge transport layers XEROX CORPORATION (US) 2009-11-17 — — US disclosed
US-20090253062-A1 LOW FRICTION ELECTROSTATOGRAPHIC IMAGING MEMBER XEROX CORPORATION (US) 2009-10-08 — — US disclosed
US-20090253063-A1 LOW FRICTION ELECTROSTATOGRAPHIC IMAGING MEMBER XEROX CORPORATION (US) 2009-10-08 — — US disclosed
US-20090253056-A1 LOW FRICTION ELECTROSTATOGRAPHIC IMAGING MEMBER XEROX CORPORATION (US) 2009-10-08 — — US disclosed
US-20090253058-A1 LOW FRICTION ELECTROSTATOGRAPHIC IMAGING MEMBER XEROX CORPORATION (US) 2009-10-08 — — US disclosed
US-20090253060-A1 LOW FRICTION ELECTROSTATOGRAPHIC IMAGING MEMBER XEROX CORPORATION (US) 2009-10-08 — — US disclosed
US-20090162637-A1 CARBON NANOTUBE FILLED POLYCARBONATE ANTI-CURL BACK COATING WITH IMPROVED ELECTRICAL AND MECHANICAL PROPERTIES XEROX CORPORATION (US) 2009-06-25 — — US disclosed
US-20080241721-A1 Photoconductors XEROX CORPORATION 2008-10-02 — — US disclosed
US-7297457-B2 Photosensitive member having an elastomeric transport layer with a protective overcoat layer XEROX CORPORATION (US) 2007-11-20 — — US disclosed
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