SCHEMBL410353

SCHEMBL410353

COC(=O)Oc1ccc(C(C)(C)c2ccc(C)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.48
NPC1 O15118 4/20 0.41
RAB9A P51151 2/20 0.41
GAA P10253 1/20 0.41
MAPT P10636 2/20 0.41
MMP13 P45452 2/20 0.41
ELANE P08246 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
ALDH1A1 P00352 1/20 0.40
TDP1 Q9NUW8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14281976 0.94 LMNA (0.43) LMNANPC1RAB9AGAAMAPT
SCHEMBL6934422 0.93 ELANE (0.46) LMNANPC1RAB9AGAAMAPT
SCHEMBL677362 0.92 LMNA (0.47) LMNANPC1RAB9AGAAMAPT
SCHEMBL15827154 0.91 LMNA (0.53) LMNANPC1RAB9AGAAMAPT
SCHEMBL14191447 0.90 LMNA (0.48) LMNANPC1RAB9AGAAMAPT
SCHEMBL14208313 0.88 LMNA (0.51) LMNANPC1RAB9AGAAMAPT
SCHEMBL16405352 0.88 MAPT (0.51) LMNANPC1RAB9AMAPTNPSR1
SCHEMBL3424216 0.88 MAPT (0.51) LMNANPC1RAB9AGAAMAPT
SCHEMBL1598492 0.87 LMNA (0.61) LMNANPC1RAB9AGAAMAPT
SCHEMBL15887448 0.86 TSHR (0.52) LMNANPC1RAB9AMAPTELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 276 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240018353-A1 POLYCARBONATE COMPOSITION, METHOD FOR THE MANUFACTURE THEREOF, AND ARTICLES FORMED THEREFROM SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2024-01-18 US disclosed
US-20240018353-A1 POLYCARBONATE COMPOSITION, METHOD FOR THE MANUFACTURE THEREOF, AND ARTICLES FORMED THEREFROM SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2024-01-18 US disclosed
WO-2023228123-A1 ANTI-DRIP POLYCARBONATE COMPOSITIONS SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2023-11-30 WO disclosed
US-20230383120-A1 TRANSPARENT FLAME RETARDANT DUCTILE COMPOSITIONS AND THIN-WALL ARTICLES THEREOF SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2023-11-30 US disclosed
US-20230383120-A1 TRANSPARENT FLAME RETARDANT DUCTILE COMPOSITIONS AND THIN-WALL ARTICLES THEREOF SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2023-11-30 US disclosed
WO-2023228124-A1 ANTI-DRIP POLYCARBONATE COMPOSITIONS SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2023-11-30 WO disclosed
EP-4282919-A1 TRANSPARENT FLAME RETARDANT DUCTILE COMPOSITIONS AND THIN-WALL ARTICLES THEREOF SHPP Global Technologies B.V. (NL) 2023-11-29 EP disclosed
US-11825587-B2 Transparent electromagnetic shielding panels and assemblies containing the same SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2023-11-21 US disclosed
US-11825587-B2 Transparent electromagnetic shielding panels and assemblies containing the same SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2023-11-21 US disclosed
US-20230357511-A1 PRODUCTION METHOD FOR POLYSILOXANE, COMPOSITION INCLUDING POLYSILOXANE, AND MOLDED BODY MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-11-09 US disclosed
US-20070191519-A1 Halogen-free polycarbonate compositions and articles formed therefrom GENERAL ELECTRIC COMPANY (US) 2007-08-16 US disclosed
US-20070191519-A1 Halogen-free polycarbonate compositions and articles formed therefrom GENERAL ELECTRIC COMPANY (US) 2007-08-16 US disclosed
WO-2007081593-A1 THERMALLY STABLE POLYCARBONATES, THERMOPLASTIC COMPOSITIONS THEREOF, AND ARTICLES FORMED THEREFROM GENERAL ELECTRIC COMPANY (US) 2007-07-19 WO disclosed
WO-2007081509-A2 POLYCARBONATE COMPOSITIONS AND ARTICLES FORMED THEREFROM, WITH MATTE SURFACES AND HIGH LIGHT TRANSMISSIONS GENERAL ELECTRIC COMPANY (US) 2007-07-19 WO disclosed
US-20070155914-A1 Polycarbonate compositions and articles formed therefrom, with matte surfaces and high light transmissions GENERAL ELECTRIC COMPANY (US) 2007-07-05 US disclosed
US-20070155914-A1 Polycarbonate compositions and articles formed therefrom, with matte surfaces and high light transmissions GENERAL ELECTRIC COMPANY (US) 2007-07-05 US disclosed
US-20070155945-A1 Thermally stable polycarbonates, thermoplastic compositions thereof, and articles formed therefrom GENERAL ELECTRIC COMPANY (US) 2007-07-05 US disclosed
US-20070155945-A1 Thermally stable polycarbonates, thermoplastic compositions thereof, and articles formed therefrom GENERAL ELECTRIC COMPANY (US) 2007-07-05 US disclosed
US-20070148055-A1 Polymerizer device for producing an aromatic polycarbonate ASAHI KASEI CHEMICALS CORPORATION (JP) 2007-06-28 US disclosed
US-20070129492-A1 POLYSILOXANE COPOLYMERS, THERMOPLASTIC COMPOSITION, AND ARTICLES FORMED THEREFROM GENERAL ELECTRIC COMPANY (US) 2007-06-07 US disclosed