SCHEMBL11950520

SCHEMBL11950520

CC12C=CC(C1)C(C(=O)CC(=O)C1C(C(=O)O)C3C=CC1(C)C3)C2C(=O)O

nearest known ligand 0.30

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
APLNR P35414 1/20 0.30
POLB P06746 1/20 0.30
APEX1 P27695 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20349477 0.88 POLB (0.38) APLNRPOLBAPEX1TDP1
SCHEMBL14074016 0.88 POLB (0.38) APLNRPOLBAPEX1TDP1
SCHEMBL1005287 0.88 POLB (0.38) APLNRPOLBAPEX1TDP1
SCHEMBL2832119 0.88 POLB (0.38) APLNRPOLBAPEX1TDP1
SCHEMBL12342891 0.79 APLNR (0.35) APLNRPOLBAPEX1TDP1
SCHEMBL6175009 0.78 PPM1B (0.36) APLNRPOLBAPEX1TDP1
SCHEMBL11108301 0.78 PPM1B (0.36) APLNRPOLB
SCHEMBL1791944 0.76 POLB (0.33) APLNRPOLBAPEX1TDP1
SCHEMBL5832895 0.72 POLB (0.44) POLBAPEX1TDP1
SCHEMBL11407715 0.71 POLB (0.34) APLNRPOLBAPEX1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8791211-B2 High refractive polymers, optical elements, and photoelectric device employing the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2014-07-29 US disclosed
US-20120197000-A1 HIGH REFRACTIVE POLYMERS, OPTICAL ELEMENTS, AND PHOTOELECTRIC DEVICE EMPLOYING THE SAME INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2012-08-02 US disclosed