Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PHGDH | O43175 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1906248 | 0.93 | GAA (0.52) | GAAPHGDHTSHRALOX15HSD17B10 | |
| SCHEMBL4000321 | 0.86 | GAA (0.50) | GAAPHGDHTSHRALOX15HSD17B10 | |
| SCHEMBL361321 | 0.86 | GAA (0.56) | GAATSHRALOX15HSD17B10ALDH1A1 | |
| SCHEMBL11952846 | 0.86 | GAA (0.61) | GAATSHRALOX15HSD17B10ALDH1A1 | |
| SCHEMBL14532458 | 0.85 | GAA (0.47) | GAATSHRALOX15HSD17B10ALDH1A1 | |
| SCHEMBL8191172 | 0.84 | PHGDH (0.47) | GAAPHGDHSMN1; SMN2CA2CA12 | |
| SCHEMBL22882728 | 0.83 | GAA (0.48) | GAATSHRALOX15HSD17B10ALDH1A1 | |
| SCHEMBL655825 | 0.82 | GAA (0.69) | GAATSHRALOX15HSD17B10ALDH1A1 | |
| SCHEMBL2075916 | 0.82 | GAA (0.63) | GAATSHRALOX15HSD17B10ALDH1A1 | |
| SCHEMBL11952850 | 0.81 | GAA (0.67) | GAATSHRALOX15HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083194-A1 | WEE1 PROTEIN KINASE DEGRADATION AGENT AND USE THEREOF | 杭州格博生物医药有限公司 | 2023-05-19 | — | — | WO | disclosed |
| EP-3322706-B1 | SUBSTITUTED PYRAZOLO[1,5-A]PYRIDINE COMPOUNDS AS RET KINASE INHIBITORS | ARRAY BIOPHARMA INC (US) | 2020-11-11 | — | — | EP | disclosed |
| WO-2018136661-A1 | SUBSTITUTED PYRAZOLO[1,5-a]PYRAZINE COMPOUNDS AS RET KINASE INHIBITORS | ANDREWS STEVEN W (US) | 2018-07-26 | — | — | WO | disclosed |
| US-8492163-B2 | Methods, mixtures, kits and compositions pertaining to analyte determination | DH TECHNOLOGIES DEVELOPMENT PTE. LTD. (SG) | 2013-07-23 | — | — | US | disclosed |
| US-8492163-B2 | Methods, mixtures, kits and compositions pertaining to analyte determination | DH TECHNOLOGIES DEVELOPMENT PTE. LTD. (SG) | 2013-07-23 | — | — | US | disclosed |
| US-20120196378-A1 | Methods, Mixtures, Kits and Compositions Pertaining to Analyte Determination | DH TECHNOLOGIES DEVELOPMNET PTE LTD. (SI) | 2012-08-02 | — | — | US | disclosed |
| US-20120196378-A1 | Methods, Mixtures, Kits and Compositions Pertaining to Analyte Determination | DH TECHNOLOGIES DEVELOPMNET PTE LTD. (SI) | 2012-08-02 | — | — | US | disclosed |
| US-7906341-B2 | Isobaric sets, mass differential labeling sets; mass spectrometry | DH TECHNOLOGIES DEVELOPMENT PTE, LTD. (SG) | 2011-03-15 | — | — | US | disclosed |
| US-20080241955-A1 | Methods, Mixtures, Kits And Compositions Pertaining To Analyte Determination | APPLERA CORPORATION (US) | 2008-10-02 | — | — | US | disclosed |
| WO-2008005846-A2 | METHODS, MIXTURES, KITS AND COMPOSITIONS PERTAINING TO ANALYTE DETERMINATION | APPLERA CORPORATION (US) | 2008-01-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080241955-A1 | Methods, Mixtures, Kits And Compositions Pertaining To Analyte Determination | SRMS, KLK3, MPO | GAA 959/4885PHGDH 2462/4885TSHR 4283/4885 |
| US-20120196378-A1 | Methods, Mixtures, Kits and Compositions Pertaining to Analyte Determination | SRMS, KLK3, MPO | GAA 959/4885PHGDH 2462/4885TSHR 4283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.