Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 10/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SCN1A | P35498 | 2/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.47 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.47 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.47 |
| ▸ | GBA1 | P04062 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10253699 | 0.88 | CNR1 (0.45) | SCN4ASCN9ALMNASCN1ASCN5A | |
| SCHEMBL10255201 | 0.86 | SCN4A (0.54) | SCN4ASCN9ALMNASCN1ASCN5A | |
| SCHEMBL12902821 | 0.84 | DPP4 (0.49) | SCN4ASCN9ALMNASCN1ASCN5A | |
| SCHEMBL10258215 | 0.84 | SCN4A (0.48) | SCN4ASCN9ALMNASCN1ASCN5A | |
| SCHEMBL12902791 | 0.84 | SCN4A (0.48) | SCN4ASCN9ALMNASCN1ASCN5A | |
| SCHEMBL11953235 | 0.84 | DPP4 (0.49) | SCN4ASCN9ALMNASCN1ASCN5A | |
| SCHEMBL27880429 | 0.84 | DPP4 (0.49) | SCN4ASCN9ALMNASCN1ASCN5A | |
| SCHEMBL11964642 | 0.84 | CNR1 (0.42) | SCN4ASCN9ALMNASCN1ASCN5A | |
| SCHEMBL11953239 | 0.83 | SCN4A (0.47) | SCN4ASCN9ALMNASCN1ASCN5A | |
| Hydrochloric Acid SCHEMBL6525283 | 0.83 | LMNA (0.49) | SCN4ASCN9ALMNASCN1ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120196933-A1 | MEXILETINE PRODRUGS | FRANKLIN RICHARD (GB) | 2012-08-02 | — | — | US | disclosed |
| US-20120196933-A1 | MEXILETINE PRODRUGS | FRANKLIN RICHARD (GB) | 2012-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120196933-A1 | MEXILETINE PRODRUGS | SLC16A1, MTPN, SLC16A3 | SCN4A 88/4885SCN9A 292/4885LMNA 311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.