Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.44 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.43 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17045217 | 0.86 | ACACB (0.47) | — | |
| SCHEMBL17045215 | 0.86 | ACACB (0.47) | — | |
| SCHEMBL17045216 | 0.86 | ACACB (0.47) | — | |
| SCHEMBL11947639 | 0.85 | ATM (0.41) | CYP1A2KMT2AANPEPSMN1; SMN2 | |
| SCHEMBL17045270 | 0.85 | ATM (0.41) | CYP1A2KMT2AANPEPSMN1; SMN2 | |
| SCHEMBL17045267 | 0.85 | ATM (0.41) | CYP1A2KMT2AANPEPSMN1; SMN2 | |
| SCHEMBL17045271 | 0.84 | SLC6A4 (0.51) | SLC6A4CYP1A2CYP2D6CYP2C19KMT2A | |
| SCHEMBL17045272 | 0.84 | SLC6A4 (0.51) | SLC6A4CYP1A2CYP2D6CYP2C19KMT2A | |
| SCHEMBL17045234 | 0.84 | TSHR (0.42) | CYP1A2KMT2ASMN1; SMN2EPHX2ALDH1A1 | |
| SCHEMBL17045269 | 0.84 | SLC6A4 (0.51) | SLC6A4CYP1A2CYP2D6CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8232315-B2 | Methods for treating drug addiction and improving addiction-related behavior | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2012-07-31 | — | — | US | disclosed |
| US-20100331332-A1 | METHODS FOR TREATING DRUG ADDICTION AND IMPROVING ADDICTION-RELATED BEHAVIOR | SK HOLDINGS CO., LTD. (KR) | 2010-12-30 | — | — | US | disclosed |
| US-20100331332-A1 | METHODS FOR TREATING DRUG ADDICTION AND IMPROVING ADDICTION-RELATED BEHAVIOR | SK HOLDINGS CO., LTD. (KR) | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331332-A1 | METHODS FOR TREATING DRUG ADDICTION AND IMPROVING ADDICTION-RELATED BEHAVIOR | CES2, SLC6A3, CHAT | LDHA 2450/4885SLC6A4 64/4885CYP1A2 3069/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.