Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.33 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11895442 | 0.85 | ALDH1A1 (0.46) | ALDH1A1KMT2ASMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL11894735 | 0.85 | ALDH1A1 (0.46) | ALDH1A1KMT2ASMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL11954841 | 0.83 | ALDH1A1 (0.43) | ALDH1A1KMT2ASMN1; SMN2KDM4EPOLB | |
| SCHEMBL11895545 | 0.78 | MAPT (0.44) | ALDH1A1SMN1; SMN2TSHRKDM4EMAPT | |
| SCHEMBL11894720 | 0.78 | MAPT (0.44) | ALDH1A1SMN1; SMN2TSHRKDM4EMAPT | |
| SCHEMBL7738890 | 0.72 | ALDH1A1 (0.50) | ALDH1A1KMT2ASMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL7564280 | 0.70 | ALDH1A1 (0.48) | ALDH1A1KMT2ASMN1; SMN2TSHRKDM4E | |
| SCHEMBL6103062 | 0.68 | ALDH1A1 (0.62) | ALDH1A1KMT2ASMN1; SMN2KDM4ETDP1 | |
| SCHEMBL13725810 | 0.67 | CACNA1D (0.44) | ALDH1A1SMN1; SMN2TSHRKDM4EMAPT | |
| SCHEMBL11895543 | 0.67 | NR3C1 (0.47) | ALDH1A1KDM4ETDP1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9006491-B2 | Structure and method for synthesizing and using dialkyl(2,4,6- or 2,6-alkoxyphenyl)phosphine and its tetrafluoroborate | ZHEJIANG UNIVERSITY (CN) | 2015-04-14 | — | — | US | disclosed |
| US-20120197030-A1 | STRUCTURE AND METHOD FOR SYNTHESIZING AND USING DIALKYL(2,4,6- OR 2,6-ALKOXYPHENYL)PHOSPHINE AND ITS TETRAFLUOROBORATE | ZHEJIANG UNIVERSITY (CN) | 2012-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120197030-A1 | STRUCTURE AND METHOD FOR SYNTHESIZING AND USING DIALKYL(2,4,6- OR 2,6-ALKOXYPHENYL)PHOSPHINE AND ITS TETRAFLUOROBORATE | PTK6, DCLK2, ERBB2 | ALDH1A1 2903/4885KMT2A 1707/4885SMN1; SMN2 4433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.