Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11954840 | 1.00 | ALDH1A1 (0.52) | ALDH1A1KMT2AHPGDHTTCA2 | |
| SCHEMBL27778154 | 1.00 | ALDH1A1 (0.52) | ALDH1A1KMT2AHPGDHTTCA2 | |
| SCHEMBL7738890 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KMT2AHPGDHTTCA2 | |
| SCHEMBL1057155 | 0.80 | ALDH1A1 (0.55) | ALDH1A1KMT2AHPGDHTTCA2 | |
| SCHEMBL24624826 | 0.77 | ALDH1A1 (0.47) | ALDH1A1KMT2AHPGDHTTCA2 | |
| SCHEMBL27729379 | 0.77 | ALDH1A1 (0.47) | ALDH1A1KMT2AHPGDHTTCA2 | |
| SCHEMBL7564290 | 0.77 | ALDH1A1 (0.52) | ALDH1A1KMT2AHPGDHTTCA2 | |
| SCHEMBL7564280 | 0.77 | ALDH1A1 (0.48) | ALDH1A1KMT2AHPGDHTTCA2 | |
| SCHEMBL11895442 | 0.76 | ALDH1A1 (0.46) | ALDH1A1KMT2AHPGDHTTCA2 | |
| SCHEMBL11894735 | 0.76 | ALDH1A1 (0.46) | ALDH1A1KMT2AHPGDHTTCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2492274-B1 | 2,4,6- OR 2,6-ALKOXYPHENYL DIALKYLPHOSPHINE, TETRAFLUOROBORATE AND USE THEREOF | UNIV ZHEJIANG (CN) | 2016-09-21 | — | — | EP | disclosed |
| US-9006491-B2 | Structure and method for synthesizing and using dialkyl(2,4,6- or 2,6-alkoxyphenyl)phosphine and its tetrafluoroborate | ZHEJIANG UNIVERSITY (CN) | 2015-04-14 | — | — | US | disclosed |
| CN-101693723-B | 3-tri-alkoxy phenyl dialkyl phosphine tetrafluoroborate and synthesis and application thereof | UNIV ZHEJIANG | 2012-09-05 | — | — | CN | disclosed |
| EP-2492274-A1 | 2,4,6- OR 2,6-ALKOXYPHENYL DIALKYLPHOSPHINE, TETRAFLUOROBORATE, PREPARATION METHOD AND USE THEREOF | Zhejiang University (CN) | 2012-08-29 | — | — | EP | disclosed |
| US-20120197030-A1 | STRUCTURE AND METHOD FOR SYNTHESIZING AND USING DIALKYL(2,4,6- OR 2,6-ALKOXYPHENYL)PHOSPHINE AND ITS TETRAFLUOROBORATE | ZHEJIANG UNIVERSITY (CN) | 2012-08-02 | — | — | US | disclosed |
| US-20120197030-A1 | STRUCTURE AND METHOD FOR SYNTHESIZING AND USING DIALKYL(2,4,6- OR 2,6-ALKOXYPHENYL)PHOSPHINE AND ITS TETRAFLUOROBORATE | ZHEJIANG UNIVERSITY (CN) | 2012-08-02 | — | — | US | disclosed |
| CN-101693723-A | 3-tri-alkoxy phenyl dialkyl phosphine tetrafluoroborate and synthesis and application thereof | UNIV ZHEJIANG | 2010-04-14 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120197030-A1 | STRUCTURE AND METHOD FOR SYNTHESIZING AND USING DIALKYL(2,4,6- OR 2,6-ALKOXYPHENYL)PHOSPHINE AND ITS TETRAFLUOROBORATE | PTK6, DCLK2, ERBB2 | ALDH1A1 2903/4885KMT2A 1707/4885HPGD 4709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.