Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ADK | P55263 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7738890 | 0.80 | ALDH1A1 (0.50) | ALDH1A1RAB9ASLC6A3KDM4EMAPT | |
| SCHEMBL7564280 | 0.77 | ALDH1A1 (0.48) | ALDH1A1RAB9ASLC6A3KDM4EMAPT | |
| SCHEMBL27729379 | 0.77 | ALDH1A1 (0.47) | ALDH1A1RAB9ASLC6A3KDM4EMAPT | |
| SCHEMBL11954846 | 0.77 | ALDH1A1 (0.52) | ALDH1A1RAB9ASLC6A3KDM4EMAPT | |
| SCHEMBL27778154 | 0.77 | ALDH1A1 (0.52) | ALDH1A1RAB9ASLC6A3KDM4EMAPT | |
| SCHEMBL24624826 | 0.77 | ALDH1A1 (0.47) | ALDH1A1RAB9ASLC6A3KDM4EMAPT | |
| SCHEMBL11954840 | 0.77 | ALDH1A1 (0.52) | ALDH1A1RAB9ASLC6A3KDM4EMAPT | |
| SCHEMBL11895442 | 0.76 | ALDH1A1 (0.46) | ALDH1A1RAB9ASLC6A3KDM4EMAPT | |
| SCHEMBL11894735 | 0.76 | ALDH1A1 (0.46) | ALDH1A1RAB9ASLC6A3KDM4EMAPT | |
| SCHEMBL11954841 | 0.72 | ALDH1A1 (0.43) | ALDH1A1RAB9ASLC6A3KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1223168-A1 | Method for the preparation of enantiomerically enriched amino and hydroxyfuranones | DSM Fine Chemicals Austria Nfg GmbH & Co KG (AT) | 2002-07-17 | — | — | EP | disclosed |