Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 10/20 | 0.70 |
| ▸ | MAPK9 | P45984 | 7/20 | 0.70 |
| ▸ | PTK2 | Q05397 | 10/20 | 0.67 |
| ▸ | CDC7 | O00311 | 1/20 | 0.56 |
| ▸ | PLK4 | O00444 | 1/20 | 0.56 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.56 |
| ▸ | AURKA | O14965 | 1/20 | 0.56 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.56 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.56 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.56 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.56 |
| ▸ | JAK2 | O60674 | 1/20 | 0.56 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.56 |
| ▸ | PAK4 | O96013 | 1/20 | 0.56 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.56 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.56 |
| ▸ | PRKCG | P05129 | 1/20 | 0.56 |
| ▸ | INSR | P06213 | 1/20 | 0.56 |
| ▸ | LCK | P06239 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12886398 | 0.92 | MAPK10 (0.69) | MAPK10MAPK9PTK2CDC7PLK4 | |
| SCHEMBL3770344 | 0.92 | MAPK10 (0.83) | MAPK10MAPK9PTK2CDC7PLK4 | |
| SCHEMBL12887601 | 0.91 | MAPK10 (0.58) | MAPK10MAPK9PTK2CDC7PLK4 | |
| SCHEMBL12887674 | 0.91 | MAPK10 (0.85) | MAPK10MAPK9PTK2CDC7PLK4 | |
| SCHEMBL12887670 | 0.91 | MAPK10 (0.85) | MAPK10MAPK9PTK2CDC7PLK4 | |
| SCHEMBL12887671 | 0.91 | MAPK10 (0.85) | MAPK10MAPK9PTK2CDC7PLK4 | |
| SCHEMBL12887665 | 0.89 | MAPK10 (0.67) | MAPK10MAPK9PTK2CDC7PLK4 | |
| SCHEMBL15964228 | 0.88 | MAPK10 (0.85) | MAPK10MAPK9PTK2CDC7PLK4 | |
| SCHEMBL12887599 | 0.83 | ULK1 (0.55) | MAPK10MAPK9PTK2CDC7PLK4 | |
| SCHEMBL12886390 | 0.83 | MAPK10 (0.70) | MAPK10MAPK9PTK2CDC7PLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120196858-A1 | METHOD OF PROMOTING APOPTOSIS AND INHIBITING METASTASIS | Poniard Pharmaceuticals ,Inc. (US) | 2012-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120196858-A1 | METHOD OF PROMOTING APOPTOSIS AND INHIBITING METASTASIS | PTK2, AIFM1, DAPK2 | MAPK10 534/4885MAPK9 768/4885PTK2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.