Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15395953 | 0.93 | NPC1 (0.48) | NPC1RAB9ALMNACYP1A2CYP3A4 | |
| SCHEMBL11956784 | 0.92 | LMNA (0.52) | NPC1RAB9ALMNACYP1A2CYP3A4 | |
| SCHEMBL11956782 | 0.90 | NPC1 (0.58) | NPC1RAB9ALMNACYP1A2CYP3A4 | |
| SCHEMBL16573654 | 0.88 | NPC1 (0.56) | NPC1RAB9ALMNACYP1A2CYP3A4 | |
| SCHEMBL11956792 | 0.86 | LMNA (0.54) | NPC1RAB9ALMNACYP1A2CYP3A4 | |
| SCHEMBL14097392 | 0.85 | NPC1 (0.56) | NPC1RAB9ALMNACYP1A2CYP3A4 | |
| SCHEMBL16270235 | 0.82 | CYP3A4 (0.54) | NPC1RAB9ALMNACYP1A2CYP3A4 | |
| SCHEMBL16270512 | 0.81 | CYP1A2 (0.55) | NPC1RAB9ALMNACYP1A2CYP3A4 | |
| SCHEMBL9420518 | 0.81 | NPC1 (0.67) | NPC1RAB9ALMNACYP1A2CYP3A4 | |
| SCHEMBL316710 | 0.81 | NPC1 (0.67) | NPC1RAB9ALMNACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160023998-A1 | HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS | BEZWADA BIOMEDICAL LLC (US) | 2016-01-28 | — | — | US | disclosed |
| US-20160023998-A1 | HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS | BEZWADA BIOMEDICAL LLC (US) | 2016-01-28 | — | — | US | disclosed |
| US-9174924-B2 | Hydrolysable linkers and cross-linkers for absorbable polymers | BEZWADA BIOMEDICAL, LLC (US) | 2015-11-03 | — | — | US | disclosed |
| US-20150259275-A1 | HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS | BEZWADA BIOMEDICAL LLC (US) | 2015-09-17 | — | — | US | disclosed |
| US-9045396-B2 | Hydrolysable linkers and cross-linkers for absorbable polymers | BEZWADA BIOMEDICAL, LLC (US) | 2015-06-02 | — | — | US | disclosed |
| US-9045396-B2 | Hydrolysable linkers and cross-linkers for absorbable polymers | BEZWADA BIOMEDICAL, LLC (US) | 2015-06-02 | — | — | US | disclosed |
| US-20140163253-A1 | HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS | BEZWADA BIOMEDICAL, LLC (US) | 2014-06-12 | — | — | US | disclosed |
| US-20140163253-A1 | HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS | BEZWADA BIOMEDICAL, LLC (US) | 2014-06-12 | — | — | US | disclosed |
| US-8664429-B2 | Hydrolysable linkers and cross-linkers for absorbable polymers | BEZWADA BIOMEDICAL, LLC (US) | 2014-03-04 | — | — | US | disclosed |
| US-20130310596-A1 | HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS | BEZWADA BIOMEDICAL, LLC (US) | 2013-11-21 | — | — | US | disclosed |
| US-20120197037-A1 | HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS | BEZWADA BIOMEDICAL, LLC (US) | 2012-08-02 | — | — | US | disclosed |
| US-8048980-B2 | Hydrolysable linkers and cross-linkers for absorbable polymers | BEZWADA BIOMEDICAL, LLC (US) | 2011-11-01 | — | — | US | disclosed |
| US-8048980-B2 | Hydrolysable linkers and cross-linkers for absorbable polymers | BEZWADA BIOMEDICAL, LLC (US) | 2011-11-01 | — | — | US | disclosed |
| US-20090082540-A1 | HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS | BEZWADA BIOMEDICAL, LLC (US) | 2009-03-26 | — | — | US | disclosed |
| US-20090082540-A1 | HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS | BEZWADA BIOMEDICAL, LLC (US) | 2009-03-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150259275-A1 | HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS | SI, KDM8, APEH | NPC1 4438/4885RAB9A 4495/4885LMNA 2710/4885 |
| US-20120197037-A1 | HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS | SI, KDM8, APEH | NPC1 4438/4885RAB9A 4495/4885LMNA 2710/4885 |
| US-20090082540-A1 | HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS | SI, KDM8, APEH | NPC1 4438/4885RAB9A 4495/4885LMNA 2710/4885 |
| US-20160023998-A1 | HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS | SI, KDM8, APEH | NPC1 4438/4885RAB9A 4495/4885LMNA 2710/4885 |
| US-20130310596-A1 | HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS | SI, KDM8, APEH | NPC1 4438/4885RAB9A 4495/4885LMNA 2710/4885 |
| US-20140163253-A1 | HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS | SI, KDM8, APEH | NPC1 4438/4885RAB9A 4495/4885LMNA 2710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.