Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 4/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21417716 | 0.82 | MDM2 (0.44) | MDM2SLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL24159396 | 0.82 | MDM2 (0.44) | MDM2SLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL6464288 | 0.79 | FASN (0.40) | FASNCYP3A4CYP2C9APPCYP2D6 | |
| SCHEMBL6464284 | 0.79 | FASN (0.40) | FASNCYP3A4CYP2C9APPCYP2D6 | |
| SCHEMBL15298462 | 0.77 | FASN (0.45) | FASNCYP3A4CYP2C9APPCYP2D6 | |
| SCHEMBL18388326 | 0.76 | PDE3B (0.36) | CYP3A4CYP2C9APPCYP2D6CYP2C19 | |
| SCHEMBL21693402 | 0.76 | PDE3B (0.36) | CYP3A4CYP2C9APPCYP2D6CYP2C19 | |
| SCHEMBL18411542 | 0.76 | PDE3B (0.36) | CYP3A4CYP2C9APPCYP2D6CYP2C19 | |
| SCHEMBL8453595 | 0.73 | FASN (0.44) | FASNCYP3A4CYP2C9APPCYP2D6 | |
| SCHEMBL8453591 | 0.73 | FASN (0.44) | FASNCYP3A4CYP2C9APPCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236390-B2 | Liquid-crystalline medium | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 2012-08-07 | — | — | US | disclosed |
| US-20100320420-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-12-23 | — | — | US | disclosed |