Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.38 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24159396 | 1.00 | MDM2 (0.44) | MDM2HTR2AHTR2CHTR2BSLC6A3 | |
| SCHEMBL11957397 | 0.82 | FASN (0.35) | MDM2HTR2AHTR2CHTR2BSLC6A3 | |
| SCHEMBL26407935 | 0.77 | MDM2 (0.47) | MDM2HTR2AHTR2CHTR2BSLC6A3 | |
| SCHEMBL10700576 | 0.73 | ESR2 (0.48) | MDM2SLC6A3TRPV1SLC6A2 | |
| SCHEMBL27394196 | 0.73 | ESR2 (0.48) | MDM2SLC6A3TRPV1SLC6A2 | |
| SCHEMBL12875742 | 0.72 | HTR2A (0.50) | MDM2HTR2AHTR2CHTR2BSLC6A3 | |
| SCHEMBL11481136 | 0.71 | SLC9A1 (0.47) | MDM2SLC6A3SLC9A1SLC6A2SLC6A4 | |
| SCHEMBL20614364 | 0.71 | HTR2A (0.37) | HTR2AHTR2CHTR2BSLC6A3SLC6A2 | |
| SCHEMBL19311575 | 0.71 | HTR2A (0.37) | HTR2AHTR2CHTR2BSLC6A3SLC6A2 | |
| SCHEMBL18472944 | 0.70 | ESR2 (0.46) | HTR2AHTR2CHTR2BSLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3387089-B1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2019-10-02 | — | — | EP | disclosed |