SCHEMBL11957692

SCHEMBL11957692

CCOC(=O)c1ccccc1C1=C2C=CC(N(CC)CC)C=C2Oc2cc(N(CC)CC)ccc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAOB P27338 1/20 0.38
▸ TSHR P16473 2/20 0.34
▸ APLNR P35414 1/20 0.34
▸ SMN1; SMN2 Q16637 4/20 0.33
▸ MAPT P10636 4/20 0.33
▸ TP53 P04637 2/20 0.33
▸ LMNA P02545 2/20 0.33
▸ NPC1 O15118 1/20 0.33
▸ NFKB1 P19838 1/20 0.33
▸ RAB9A P51151 1/20 0.33
▸ NFKB2 Q00653 1/20 0.33
▸ RELA Q04206 1/20 0.33
▸ L3MBTL1 Q9Y468 2/20 0.33
▸ MEN1 O00255 2/20 0.33
▸ KMT2A Q03164 2/20 0.33
▸ PGR P06401 1/20 0.33
▸ ALDH1A1 P00352 4/20 0.32
▸ GAA P10253 2/20 0.32
▸ HSD17B10 Q99714 3/20 0.32
▸ KDM4E B2RXH2 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12093970 0.93 ALDH1A1 (0.36) MAOBTSHRAPLNRSMN1; SMN2MAPT
SCHEMBL16489114 0.92 CA12 (0.36) MAOBTSHRAPLNRSMN1; SMN2MAPT
Hydrochloric Acid SCHEMBL5539689 0.91 TSHR (0.38) TSHRAPLNRSMN1; SMN2MAPTTP53
Hydrochloric Acid SCHEMBL5547769 0.90 SCN1A (0.36) TSHRAPLNRSMN1; SMN2MAPTTP53
SCHEMBL3267635 0.89 MEN1 (0.41) MAOBAPLNRSMN1; SMN2MAPTTP53
SCHEMBL30887127 0.89 SCN1A (0.31) APLNRSCN1ASCN2ASCN3A
SCHEMBL30887124 0.89 SCN1A (0.31) APLNRSCN1ASCN2ASCN3A
SCHEMBL18888028 0.89 SCN1A (0.31) APLNRSCN1ASCN2ASCN3A
SCHEMBL12118354 0.89 MAPT (0.35) MAOBAPLNRSMN1; SMN2MAPTTP53
SCHEMBL17448856 0.87 TSHR (0.34) TSHRSMN1; SMN2MAPTTP53LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8236472-B2 Image forming method KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2012-08-07 — — US disclosed
US-20100136476-A1 IMAGE FORMING METHOD KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2010-06-03 — — US disclosed
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