Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | APLNR | P35414 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11957692 | 0.92 | MAOB (0.38) | CA12CA9MAPTSMN1; SMN2NPC1 | |
| SCHEMBL12093970 | 0.91 | ALDH1A1 (0.36) | CA12CA9MAPTSMN1; SMN2NPC1 | |
| SCHEMBL3267635 | 0.90 | MEN1 (0.41) | MAPTSMN1; SMN2NPC1LMNARAB9A | |
| SCHEMBL12118354 | 0.89 | MAPT (0.35) | CA12CA9MAPTSMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL5539689 | 0.88 | TSHR (0.38) | CA12CA9MAPTSMN1; SMN2NPC1 | |
| SCHEMBL14039656 | 0.87 | ALDH1A1 (0.35) | CA12CA9MAPTSMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL5547769 | 0.87 | SCN1A (0.36) | MAPTSMN1; SMN2NPC1LMNARAB9A | |
| SCHEMBL18760512 | 0.86 | RAB9A (0.36) | MAPTSMN1; SMN2NPC1LMNARAB9A | |
| SCHEMBL18888028 | 0.86 | SCN1A (0.31) | APLNR | |
| SCHEMBL12130884 | 0.83 | APLNR (0.32) | APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9289508-B2 | Environmentally sensitive compositions and methods of use in the treatment and diagnosis of tumors | UNIVERSITY OF RHODE ISLAND (US) | 2016-03-22 | — | — | US | disclosed |
| US-20150051153-A1 | Environmentally Sensitive Compositions | UNIVERSITY OF RHODE ISLAND BOARD OF TRUSTEES | 2015-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150051153-A1 | Environmentally Sensitive Compositions | PHLPP1, PHLPP2, FABP2 | CA12 1175/4885CA9 1028/4885MAPT 3026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.