Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.78 |
| ▸ | NPC1 | O15118 | 6/20 | 0.78 |
| ▸ | HPGD | P15428 | 5/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.78 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.78 |
| ▸ | CA12 | O43570 | 3/20 | 0.76 |
| ▸ | CA1 | P00915 | 3/20 | 0.76 |
| ▸ | CA9 | Q16790 | 3/20 | 0.76 |
| ▸ | CASP3 | P42574 | 1/20 | 0.70 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.70 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.70 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.70 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | GLA | P06280 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12987100 | 0.88 | ALDH1A1 (1.00) | RAB9AKDM4EALDH1A1NPC1HPGD | |
| SCHEMBL8513693 | 0.87 | CA12 (0.81) | RAB9AKDM4EALDH1A1NPC1HPGD | |
| SCHEMBL9612721 | 0.87 | CA9 (1.00) | RAB9AKDM4EALDH1A1NPC1HPGD | |
| SCHEMBL11230052 | 0.86 | CA12 (0.71) | RAB9AKDM4EALDH1A1NPC1HPGD | |
| SCHEMBL30449676 | 0.85 | CA12 (1.00) | RAB9AKDM4EALDH1A1NPC1HPGD | |
| SCHEMBL8516165 | 0.85 | CA12 (1.00) | RAB9AKDM4EALDH1A1NPC1HPGD | |
| SCHEMBL15747020 | 0.84 | CA12 (0.76) | RAB9AKDM4EALDH1A1NPC1HPGD | |
| SCHEMBL22685138 | 0.84 | CA12 (0.76) | RAB9AKDM4EALDH1A1NPC1HPGD | |
| SCHEMBL20435346 | 0.83 | KDM4E (0.78) | RAB9AKDM4EALDH1A1NPC1HPGD | |
| SCHEMBL11232995 | 0.83 | CA12 (0.74) | RAB9AKDM4EALDH1A1NPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2424524-A1 | TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS | University Court of The University of Dundee (GB) | 2012-03-07 | — | — | EP | disclosed |
| WO-2010125350-A1 | TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2010-11-04 | — | — | WO | disclosed |