SCHEMBL8516165

SCHEMBL8516165

CC(=O)Nc1ccc2c(C)cc(=O)oc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 1.00
CA1 P00915 3/20 1.00
CA9 Q16790 3/20 1.00
RAB9A P51151 8/20 0.69
NPC1 O15118 8/20 0.69
KDM4E B2RXH2 6/20 0.69
ALDH1A1 P00352 6/20 0.69
HPGD P15428 5/20 0.69
SMN1; SMN2 Q16637 3/20 0.69
HSD17B10 Q99714 2/20 0.69
GAA P10253 2/20 0.67
GLA P06280 1/20 0.67
MAP2K1 Q02750 1/20 0.67
KMT2A Q03164 2/20 0.64
MEN1 O00255 1/20 0.64
TDP1 Q9NUW8 2/20 0.63
CTDSP1 Q9GZU7 2/20 0.62
MAPT P10636 1/20 0.62
NPSR1 Q6W5P4 1/20 0.62
CACNA1B Q00975 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30449676 1.00 CA12 (1.00) CA12CA1CA9RAB9ANPC1
SCHEMBL8513693 0.89 CA12 (0.81) CA12CA1CA9RAB9ANPC1
SCHEMBL15747020 0.87 CA12 (0.76) CA12CA1CA9RAB9ANPC1
SCHEMBL22685138 0.87 CA12 (0.76) CA12CA1CA9RAB9ANPC1
SCHEMBL15607719 0.87 CA12 (0.76) CA12CA1CA9RAB9ANPC1
SCHEMBL7915781 0.86 CA12 (0.75) CA12CA1CA9RAB9ANPC1
SCHEMBL30862484 0.86 CA12 (0.75) CA12CA1CA9RAB9ANPC1
SCHEMBL119578 0.85 RAB9A (0.78) CA12CA1CA9RAB9ANPC1
SCHEMBL11232995 0.85 CA12 (0.74) CA12CA1CA9RAB9ANPC1
SCHEMBL19278118 0.85 CA12 (0.74) CA12CA1CA9RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119432113-A Aza-hemicyanine dye and application thereof 广西师范大学 2025-02-14 CN claimed
US-11852582-B2 Automatic photocurrent spectrum measurement system based on fourier infrared spectrometer EAST CHINA NORMAL UNIVERSITY (CN) 2023-12-26 US claimed
CN-116242697-A Uniaxial compression mechanical property testing method for battery electrode material particles 北京理工大学 2023-06-09 CN claimed
US-20220381683-A1 AUTOMATIC PHOTOCURRENT SPECTRUM MEASUREMENT SYSTEM BASED ON FOURIER INFRARED SPECTROMETER EAST CHINA NORMAL UNIVERSITY (CN) 2022-12-01 US claimed
EP-2771488-B1 CARBONIC ANHYDRASE IX-RELATED MARKERS AND USE THEREOF SIGNALCHEM LIFESCIENCES CORP (CA) 2018-03-28 EP claimed
US-20140148400-A1 CARBONIC ANHYDRASE INHIBITORS WITH ANTIMETASTATIC ACTIVITY METASIGNAL THERAPEUTICS INC. (CA) 2014-05-29 US claimed
WO-2012070024-A1 CARBONIC ANHYDRASE INHIBITORS WITH ANTIMETASTATIC ACTIVITY METASIGNAL THERAPEUTICS INC. (CA) 2012-05-31 WO claimed
CN-120737184-A NA-CATH modified peptide and application thereof in preparation of antibacterial drugs 中国医学科学院医药生物技术研究所 2025-10-03 CN disclosed
US-20250305102-A1 STEEL SHEET NIPPON STEEL CORPORATION (JP) 2025-10-02 US disclosed
EP-3603648-B1 COMPLEX OF NUCLEIC ACID MEDICINE AND MULTIBRANCHED LIPID SHIONOGI & CO (JP) 2025-09-17 EP disclosed
US-12415835-B2 Peptide-compound cyclization method CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-09-16 US disclosed
US-12371428-B2 Pyridone compounds and methods of use EXELIXIS, INC. (US) 2025-07-29 US disclosed
WO-2025109338-A1 SALT FORMS OF A CHROMENE COMPOUND Ontrack Therapeutics Limited (GB) 2025-05-30 WO disclosed
US-20140148400-A1 CARBONIC ANHYDRASE INHIBITORS WITH ANTIMETASTATIC ACTIVITY METASIGNAL THERAPEUTICS INC. (CA) 2014-05-29 US disclosed
WO-2012070024-A1 CARBONIC ANHYDRASE INHIBITORS WITH ANTIMETASTATIC ACTIVITY METASIGNAL THERAPEUTICS INC. (CA) 2012-05-31 WO disclosed
WO-2012070024-A1 CARBONIC ANHYDRASE INHIBITORS WITH ANTIMETASTATIC ACTIVITY METASIGNAL THERAPEUTICS INC. (CA) 2012-05-31 WO disclosed
EP-1926757-B1 ANTIBODY-COMB POLYMER CONJUGATE UCB PHARMA SA (BE) 2012-02-22 EP disclosed
CN-101712666-A Preparation method of laser dye 7-amino-4-methylcoumarin TIANJIN CHEM REAGENT RES INST 2010-05-26 CN disclosed
EP-2014285-A1 NPYY5 antagonists Shionogi&Co., Ltd. (JP) 2009-01-14 EP disclosed
US-20080138817-A1 Novel Functional Peptide Nucleic Acid Monomer and Process for Producing the Same CREDIA JAPAN CO., LTD. (JP) 2008-06-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140148400-A1 CARBONIC ANHYDRASE INHIBITORS WITH ANTIMETASTATIC ACTIVITY CA7, CA4, CA2 CA12 10/4885CA1 5/4885CA9 4/4885
US-12371428-B2 Pyridone compounds and methods of use PDXK, PLK2, MAP4K2 CA12 4882/4885CA1 4815/4885CA9 4885/4885
US-20080138817-A1 Novel Functional Peptide Nucleic Acid Monomer and Process for Producing the Same NSUN3, RNGTT, NSUN2 CA12 1995/4885CA1 3208/4885CA9 2364/4885
US-12415835-B2 Peptide-compound cyclization method VIP, NGLY1, GLP1R CA12 1113/4885CA1 1024/4885CA9 1496/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.