⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene SCHEMBL27741856 | 0.79 | KDM4E (0.52) | — | |
| SCHEMBL409030 | 0.78 | KDM4E (0.55) | — | |
| SCHEMBL4728794 | 0.76 | KDM4E (0.52) | — | |
| Hydrochloric Acid SCHEMBL28670387 | 0.76 | KDM4E (0.53) | — | |
| Phosphine SCHEMBL17979775 | 0.76 | KDM4E (0.53) | — | |
| SCHEMBL449878 | 0.75 | — | — | |
| SCHEMBL6243649 | 0.75 | CES2 (0.43) | — | |
| SCHEMBL8601029 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL8052161 | 0.74 | KDM4E (0.50) | — | |
| SCHEMBL15561907 | 0.74 | KDM4E (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 5521 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4399206-A1 | PAPD5 AND/OR PAPD7 INHIBITING 4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID DERIVATIVES | Redona Therapeutics, Inc. (US) | 2024-07-17 | — | — | EP | claimed |
| CN-118201914-A | 4-Oxo-1, 4-dihydroquinoline-3-carboxylic acid derivatives as PAPD5 and/or PAPD7 inhibitors | 雷多纳治疗公司 | 2024-06-14 | — | — | CN | claimed |
| WO-2023039089-A1 | PAPD5 AND/OR PAPD7 INHIBITING 4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID DERIVATIVES | TWENTYEIGHT-SEVEN, INC. (US) | 2023-03-16 | — | — | WO | claimed |
| WO-2022240213-A1 | NOVEL BENZOTHIAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF FOR PREVENTION OR TREATMENT OF LIVER DISEASE | 에이치케이이노엔 주식회사 | 2022-11-17 | — | — | WO | claimed |
| CN-108463460-B | Microbiocidal oxadiazole derivatives | 先正达参股股份有限公司 | 2022-10-28 | — | — | CN | claimed |
| EP-3897644-A1 | COMPOUNDS THAT PARTICIPATE IN COOPERATIVE BINDING AND USES THEREOF | Revolution Medicines, Inc. (US) | 2021-10-27 | — | — | EP | claimed |
| CN-113498342-A | Compounds involved in synergistic binding and uses thereof | 锐新医药公司 | 2021-10-12 | — | — | CN | claimed |
| CN-112384515-A | Imidazopyrimidines and triazolopyrimidines as A2A/A2B inhibitors | 因赛特公司 | 2021-02-19 | — | — | CN | claimed |
| US-20200197391-A1 | COMPOUNDS THAT PARTICIPATE IN COOPERATIVE BINDING AND USES THEREOF | Revolution Medicines, Inc. | 2020-06-25 | — | — | US | claimed |
| WO-2020132597-A1 | COMPOUNDS THAT PARTICIPATE IN COOPERATIVE BINDING AND USES THEREOF | Revolution Medicines, Inc. (US) | 2020-06-25 | — | — | WO | claimed |
| US-5616601-A | 1,2-aryl and heteroaryl substituted imidazolyl compounds for the treatment of inflammation | GD SEARLE & CO (US) | 1997-04-01 | — | — | US | claimed |
| US-5594020-A | FUNGICIDE | BASF AKTIENGESELLSCHAFT (DE) | 1997-01-14 | — | — | US | claimed |
| EP-0699192-A1 | SUBSTITUTED OXAZOLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-03-06 | — | — | EP | claimed |
| WO-1996003388-A1 | 1,2-SUBSTITUTED IMIDAZOLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-02-08 | — | — | WO | claimed |
| US-5376655-A | Elastase inhibitor | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-12-27 | — | — | US | claimed |
| WO-1994027980-A1 | SUBSTITUTED OXAZOLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1994-12-08 | — | — | WO | claimed |
| EP-0222608-B1 | DERIVATIVES OF P-GUANIDINOBENZOIC ACID AND PHARMACEUTICAL AGENTS CONTAINING THEM AS ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 1991-09-11 | — | — | EP | claimed |
| US-4975464-A | ADMINISTERING DERIVATIVES OF P-GUANIDINOBENZOIC ACID | IMAKI KATSUHIRO (JP) | 1990-12-04 | — | — | US | claimed |
| EP-0222608-A2 | Derivatives of p-guanidinobenzoic acid and pharmaceutical agents containing them as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 1987-05-20 | — | — | EP | claimed |
| US-4233454-A | Cyclopentane acetic acid derivatives | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1980-11-11 | — | — | US | claimed |