SCHEMBL409030

SCHEMBL409030

c1ccc(Oc2ccccn2)nc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.55
LMNA P02545 3/20 0.55
CCR1 P32246 2/20 0.55
CCR5 P51681 2/20 0.55
CCR8 P51685 2/20 0.55
CYP1A2 P05177 1/20 0.55
POLB P06746 1/20 0.55
METAP1 P53582 1/20 0.55
BLM P54132 1/20 0.55
HIF1A Q16665 1/20 0.55
DOHH Q9BU89 1/20 0.55
P4HTM Q9NXG6 1/20 0.55
NPC1 O15118 3/20 0.46
TDP1 Q9NUW8 3/20 0.46
TP53 P04637 2/20 0.46
ALOX15 P16050 2/20 0.46
HTT P42858 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
RAB9A P51151 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28670387 0.97 KDM4E (0.53) KDM4ELMNACCR1CCR5CCR8
Phosphine SCHEMBL17979775 0.97 KDM4E (0.53) KDM4ELMNACCR1CCR5CCR8
Ethylene SCHEMBL27741856 0.95 KDM4E (0.52) KDM4ELMNACCR1CCR5CCR8
SCHEMBL12129562 0.90 KDM4E (0.58) KDM4ELMNACCR1CCR5CCR8
SCHEMBL11138427 0.87 KDM4E (0.66) KDM4ELMNACCR1CCR5CCR8
SCHEMBL11143982 0.87 PTGS2 (0.57) KDM4ELMNACCR1CCR5CCR8
SCHEMBL9384543 0.87 KDM4E (0.50) KDM4ELMNACCR1CCR5CCR8
SCHEMBL22061563 0.85 KDM4E (0.48) KDM4ELMNACCR1CCR5CCR8
SCHEMBL9359315 0.85 KDM4E (0.63) KDM4ELMNACCR1CCR5CCR8
SCHEMBL147539 0.85 LOXL2 (0.52) KDM4ELMNACCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 662 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250296922-A1 POLYSUBSTITUTED PYRROLIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF SHANGHAI WENNAI THERAPEUTICS CO LTD (CN) 2025-09-25 US claimed
US-12331027-B2 Herbicidal pyridylethers BASF SE 2025-06-17 US claimed
CN-111356684-B Herbicidal pyridyl ethers 巴斯夫欧洲公司 2025-03-28 CN claimed
WO-2025021115-A1 POLYSUBSTITUTED PYRROLIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF 上海闻耐医药科技有限公司 2025-01-30 WO claimed
CN-118580513-B Preparation method and application of N-pyridyl naphthalimide coordination polymer 曲靖师范学院 2024-10-22 CN claimed
CN-118754821-A Meta-diamide compound, and salts, preparation method, composition and application thereof acceptable as pesticides 深圳大学 2024-10-11 CN claimed
CN-118580513-A Preparation method and application of N-pyridyl naphthalimide coordination polymer 曲靖师范学院 2024-09-03 CN claimed
EP-4326892-A1 METHOD FOR SELECTING ECOBIOLOGICAL TOPICAL COMPOSITIONS AND INGREDIENTS CAPABLE OF RESTORING OR REINFORCING THE SKIN MICROBIOTA NAOS Institute of Life Science (FR) 2024-02-28 EP claimed
CN-116496324-A Ruthenium complex, preparation method thereof and application thereof in alkylation reaction of indole and alcohol 河北师范大学 2023-07-28 CN claimed
CN-116157404-A Heteroaryl substituted spiropiperidinyl derivatives and pharmaceutical uses thereof 诺华股份有限公司 2023-05-23 CN claimed
CN-87106804-A Imidazopyridine derivatives, the pharmaceutical compositions that contains imidazopyridine derivatives and their preparation method 1988-05-18 CN claimed
EP-0266890-A1 Imidazopyridine derivatives, their production, and pharmaceutical compositions containing them YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1988-05-11 EP claimed
US-4695575-A ANTIHISTAMINES JANSSEN PHARMACEUTICA, N.V. (BE) 1987-09-22 US claimed
EP-0206415-A2 (4-Piperidinylmethyl and -hetero)purines JANSSEN PHARMACEUTICA N.V. (BE) 1986-12-30 EP claimed
EP-0206581-A2 Agriculturally-useful sulfonamides ELI LILLY AND COMPANY (US) 1986-12-30 EP claimed
CN-86103621-A The method of the sulphonamide of preparation agriculturally useful 1986-12-10 CN claimed
EP-0003771-B1 CARBOSTYRILE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Dr. Karl Thomae GmbH (DE) 1982-10-20 EP claimed
US-4329347-A Cardiotonic and antithrombotic sulfur-containing derivatives of carbostyril BOEHRINGER INGELHEIM GMBH (DE) 1982-05-11 US claimed
US-4309210-A HERBICIDE AND SAFENING AGENT CIBA-GEIGY CORPORATION (US) 1982-01-05 US claimed
US-4153795-A Cobalt pyridyl catalysts for hydroformylation DIRECTOR-GENERAL OF THE AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1979-05-08 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12331027-B2 Herbicidal pyridylethers DDT, PLPBP, PNPO KDM4E 1166/4885LMNA 3155/4885CCR1 3453/4885
US-20250296922-A1 POLYSUBSTITUTED PYRROLIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF SCN8A, SCN11A, TRPV1 KDM4E 2867/4885LMNA 2967/4885CCR1 3992/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.