Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14438153 | 0.92 | TSHR (0.35) | TSHRLMNATYRALDH1A1HDAC1 | |
| SCHEMBL24136334 | 0.82 | TSHR (0.52) | TSHRLMNAALDH1A1HDAC1CA1 | |
| SCHEMBL17875011 | 0.80 | CYP2A6 (0.38) | TSHRALDH1A1CYP1A2CA1CA2 | |
| SCHEMBL24564597 | 0.80 | ESR1 (0.54) | TSHRLMNATYRALDH1A1KIF11 | |
| SCHEMBL246162 | 0.79 | ALDH1A1 (0.46) | TSHRALDH1A1HDAC1MAPTMAPK1 | |
| SCHEMBL424728 | 0.76 | TSHR (0.73) | TSHRLMNATYRALDH1A1HDAC1 | |
| SCHEMBL1243634 | 0.74 | SLC22A2 (0.52) | TSHRLMNATYRALDH1A1HDAC1 | |
| SCHEMBL21304588 | 0.73 | TSHR (0.42) | TSHRLMNATYRALDH1A1HDAC1 | |
| SCHEMBL16510924 | 0.73 | PDE2A (0.37) | TSHRLMNAALDH1A1KIF11CYP1A2 | |
| SCHEMBL10290029 | 0.72 | TSHR (0.44) | TSHRLMNAALDH1A1RARBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1995265-B1 | POLYARYLENE AND PROCESS FOR PRODUCING THE SAME | SUMITOMO CHEMICAL CO (JP) | 2012-08-01 | — | — | EP | disclosed |