SCHEMBL424728

SCHEMBL424728

CC(C)(C)c1ccc(C(C)(C)C)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.73
LMNA P02545 1/20 0.69
TYR P14679 1/20 0.69
KIF11 P52732 2/20 0.55
ALDH1A1 P00352 4/20 0.52
BCHE P06276 4/20 0.50
ACHE P22303 4/20 0.50
HPGD P15428 2/20 0.50
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
MAPT P10636 1/20 0.50
MAPK1 P28482 1/20 0.50
HDAC1 Q13547 1/20 0.50
ALOX15 P16050 1/20 0.50
HSD17B10 Q99714 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
SLC22A2 O15244 1/20 0.50
SLC22A1 O15245 1/20 0.50
SLC22A3 O75751 1/20 0.50
SRD5A2 P31213 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3423876 0.89 KIF11 (0.70) TSHRLMNATYRKIF11ALDH1A1
SCHEMBL17923896 0.89 TSHR (0.61) TSHRLMNATYRKIF11ALDH1A1
SCHEMBL1538330 0.89 TSHR (0.61) TSHRLMNATYRKIF11ALDH1A1
SCHEMBL26915 0.89 KIF11 (0.70) TSHRLMNATYRKIF11ALDH1A1
SCHEMBL166690 0.86 TSHR (1.00) TSHRLMNATYRKIF11ALDH1A1
SCHEMBL11210257 0.86 TSHR (0.58) TSHRLMNATYRKIF11ALDH1A1
SCHEMBL1931781 0.86 KIF11 (0.67) TSHRLMNATYRKIF11ALDH1A1
SCHEMBL5495871 0.86 TSHR (1.00) TSHRLMNATYRKIF11ALDH1A1
SCHEMBL10620533 0.83 LMNA (0.60) TSHRLMNATYRKIF11ALDH1A1
SCHEMBL70053 0.83 TRPV1 (0.55) TSHRLMNATYRKIF11ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 564 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117362826-B Modifier, modified asphalt and preparation method thereof 湖北工业大学 2026-05-15 CN claimed
US-20240400784-A1 Method for Screening Solvent for Extracting Polyvinyl Chloride, Method for Recycling Waste, Recycled Polyvinyl Chloride, and Composition LG CHEM, LTD. (KR) 2024-12-05 US claimed
US-20240392094-A1 Method for Screening Solvent for Polyvinyl Chloride Extraction, Recycling Method for Waste Material, and Recycled Polyvinyl Chloride and Composition LG CHEM, LTD. (KR) 2024-11-28 US claimed
CN-118956473-A Stainless steel cutting fluid and preparation method thereof 东莞市英思漫润滑科技有限公司 2024-11-15 CN claimed
CN-115028518-B Preparation and application of 2,2' -oxo-bis-1, 4-di-tert-butylbenzene 南方海洋科学与工程广东省实验室(广州) 2024-07-23 CN claimed
CN-117897440-A Method for screening solvent for extraction of polyvinyl chloride, method for recycling waste material, recycled polyvinyl chloride and composition 株式会社LG化学 2024-04-16 CN claimed
CN-117384692-B Concrete release agent and preparation method thereof 南京福盛新材料有限公司 2024-03-19 CN claimed
CN-117384692-A Concrete release agent and preparation method thereof 南京福盛新材料有限公司 2024-01-12 CN claimed
CN-117362826-A Modifier, modified asphalt and preparation method thereof 湖北工业大学 2024-01-09 CN claimed
CN-115108880-B Method for separating methylcyclopentane and methylenecyclopentane 万华化学集团股份有限公司 2023-12-19 CN claimed
WO-2005118598-A1 PROCESS FOR MAKING HALOORGANOALKOXYSILANES GENERAL ELECTRIC COMPANY (US) 2005-12-15 WO claimed
US-6872845-B2 Process for making haloorganoalkoxysilanes GENERAL ELECTRIC COMPANY (US) 2005-03-29 US claimed
EP-0980901-B1 Non-hazing UV curable powder coatings containing crystalline resins MORTON INT INC (US) 2004-11-10 EP claimed
US-20040176627-A1 Process for making haloorganoalkoxysilanes CROMPTON CORPORATION 2004-09-09 US claimed
EP-0841331-B1 New epoxides, process for their preparation and their use for the preparation of perfume ingredients FIRMENICH & CIE (CH) 2003-01-08 EP claimed
US-6503662-B1 Tert-butylbenzene derivative prevents oxidation and decomposition of solvent at the time of charging which causes decreased battery characteristics UBE INDUSTRIES, LTD. (JP) 2003-01-07 US claimed
US-6451937-B1 BY THERMALLY REACTING A FUNCTIONALIZING REAGENT AND THE HYDROCARBON IN THE PRESENCE OF A TRANSITION METAL COORDINATION CATALYST SHELL OIL COMPANY 2002-09-17 US claimed
US-20010039349-A1 Selective, Catalytic, thermal functionalization of secondary or aromatic C-H cyclic hydrocarbon bonds SHELL OIL COMPANY 2001-11-08 US claimed
EP-0192492-B1 PEPTIDES CONTAINING AN ALIPHATIC-AROMATIC KETONE SIDE CHAIN THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 1992-01-02 EP claimed
US-4556750-A DIALKYLATION OF BENZENE WITH ISOBUTYLENE IN THE PRESENCE OF A CATALYST PHILLIPS PETROLEUM COMPANY (US) 1985-12-03 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040176627-A1 Process for making haloorganoalkoxysilanes HPD, HDHD5, HAO2 TSHR 3912/4885LMNA 3318/4885TYR 141/4885
US-20010039349-A1 Selective, Catalytic, thermal functionalization of secondary or aromatic C-H cyclic hydrocarbon bonds AHR, PAH, HRH3 TSHR 1650/4885LMNA 2081/4885TYR 13/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.