SCHEMBL11960784

SCHEMBL11960784

CC(OCCC1CCCCC1)Oc1ccc([C@@H](CC(C)(C)C)C(C)(C)C)cc1

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 1/20 0.38
PPARG P37231 1/20 0.34
PPARD Q03181 1/20 0.34
PPARA Q07869 1/20 0.34
HPGD P15428 5/20 0.33
MEN1 O00255 1/20 0.33
MITF O75030 1/20 0.33
KMT2A Q03164 1/20 0.33
FFAR1 O14842 1/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HRH3 Q9Y5N1 1/20 0.31
GRM2 Q14416 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11960820 1.00 NFE2L2 (0.38) NFE2L2PPARGPPARDPPARAHPGD
SCHEMBL11960798 0.93 HRH3 (0.37) NFE2L2HPGDMEN1MITFKMT2A
SCHEMBL11960893 0.93 HRH3 (0.37) NFE2L2HPGDMEN1MITFKMT2A
SCHEMBL15436227 0.90 NFE2L2 (0.38) NFE2L2PPARGPPARDPPARAHPGD
SCHEMBL11960989 0.89 SIGMAR1 (0.30)
SCHEMBL11961099 0.89 FFAR1 (0.37) NFE2L2HPGDMEN1MITFKMT2A
SCHEMBL14220827 0.88 NFE2L2 (0.38) NFE2L2PPARGPPARDPPARAHPGD
SCHEMBL26158132 0.86 NFE2L2 (0.40) NFE2L2PPARGPPARDPPARAHPGD
SCHEMBL11961313 0.85 PPARG (0.30) PPARGPPARDPPARA
SCHEMBL13359778 0.85 NFE2L2 (0.41) NFE2L2PPARGPPARDPPARAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1367439-B1 Radiation-sensitive composition FUJIFILM CORP (JP) 2012-08-01 EP disclosed