SCHEMBL1196080

SCHEMBL1196080

CCCCCCC1C=CC(CCCCC)C(C(=O)O)C1C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNTT P04053 1/20 0.44
ALOX5 P09917 1/20 0.42
GPR84 Q9NQS5 7/20 0.40
PPARG P37231 7/20 0.40
PPARD Q03181 7/20 0.40
PPARA Q07869 7/20 0.40
HDAC11 Q96DB2 5/20 0.40
TSHR P16473 5/20 0.40
ALDH1A1 P00352 4/20 0.40
PTPN1 P18031 3/20 0.40
TLR2 O60603 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
FABP4 P15090 2/20 0.40
S1PR3 Q99500 2/20 0.40
SLC22A6 Q4U2R8 1/20 0.40
SLC22A8 Q8TCC7 1/20 0.40
MEN1 O00255 1/20 0.40
ESR1 P03372 1/20 0.40
ALOX15 P16050 1/20 0.40
PDE4A P27815 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11869827 0.93 DNTT (0.40) DNTTALOX5GPR84PPARGPPARD
SCHEMBL11866012 0.91 ALOX5 (0.47) ALOX5GPR84PPARGPPARDPPARA
SCHEMBL11421643 0.91 GPR84 (0.57) ALOX5GPR84PPARGPPARDPPARA
SCHEMBL11428058 0.91 GPR84 (0.57) ALOX5GPR84PPARGPPARDPPARA
SCHEMBL13237090 0.88 GPR84 (0.52) ALOX5GPR84PPARGPPARDPPARA
SCHEMBL11866003 0.84 DNTT (0.35) DNTTALOX5GPR84PPARGPPARD
SCHEMBL17308136 0.83 AKR1B1 (0.47) ALOX5GPR84PPARGPPARDPPARA
SCHEMBL5050320 0.82 ALOX5 (0.43) DNTTALOX5PPARGALDH1A1S1PR3
SCHEMBL11427538 0.82 TSHR (0.49) DNTTALOX5GPR84PPARGPPARD
SCHEMBL11423125 0.82 TSHR (0.49) DNTTALOX5GPR84PPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8729189-B2 Propylene-based block copolymer, composition containing the copolymer, and molded products obtained therefrom MITSUI CHEMICALS, INC. (JP) 2014-05-20 US disclosed
US-20110172353-A1 PROPYLENE-BASED BLOCK COPOLYMER, COMPOSITION CONTAINING THE COPOLYMER, AND MOLDED PRODUCTS OBTAINED THEREFROM MITSUI CHEMICALS, INC. (JP) 2011-07-14 US disclosed
EP-2330139-A1 PROPYLENE-BASED BLOCK COPOLYMER AND COMPOSITION CONTAINING SAID COPOLYMER, AND MOLDED BODY OBTAINED THEREFROM Mitsui Chemicals, Inc. (JP) 2011-06-08 EP disclosed
US-7888438-B2 A solid titanium catalyst component comprising titanium, magnesium, halogen, and a C5-C10 carbocyclic diester, and an organometallic component; moldable polyolefins having broad molecular weight distribution MITSUI CHEMICALS, INC. (JP) 2011-02-15 US disclosed
US-20080125555-A1 Catalyst for olefin polymerization and process for olefin polymerization MITSUI CHEMICALS, INC. (JP) 2008-05-29 US disclosed