SCHEMBL11960804

SCHEMBL11960804

CC(OCc1ccccc1)Oc1ccc(C(CC(C)(C)C)C(C)(C)C)cc1

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 1/20 0.40
ALOX5 P09917 1/20 0.37
LMNA P02545 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CNR2 P34972 1/20 0.36
PRKCA P17252 1/20 0.34
PRKCD Q05655 1/20 0.34
KAT2B Q92831 1/20 0.33
MAPT P10636 1/20 0.33
BCHE P06276 1/20 0.33
MEN1 O00255 1/20 0.33
MITF O75030 1/20 0.33
KMT2A Q03164 1/20 0.33
RCE1 Q9Y256 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11961098 0.88 AGXT (0.36) LMNACNR2MAPT
SCHEMBL11961052 0.87 FFAR1 (0.36) CNR2
SCHEMBL14318499 0.87 FFAR1 (0.36) CNR2
SCHEMBL11960780 0.85 PPARG (0.35) L3MBTL1
SCHEMBL11961011 0.84 TDP1 (0.40) L3MBTL1
SCHEMBL16389703 0.81 AOC3 (0.45) AOC3ALOX5LMNAL3MBTL1CNR2
SCHEMBL10077945 0.81 LMNA (0.50) ALOX5LMNAL3MBTL1PRKCAPRKCD
SCHEMBL14564536 0.81 LMNA (0.33) LMNA
SCHEMBL10170753 0.81 IDO1 (0.44) AOC3ALOX5LMNAL3MBTL1CNR2
SCHEMBL14584566 0.79 AOC3 (0.33) AOC3L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1367439-B1 Radiation-sensitive composition FUJIFILM CORP (JP) 2012-08-01 EP disclosed