SCHEMBL1196118

SCHEMBL1196118

O=C(O)c1ccccc1N=NI

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ IDE P14735 1/20 0.58
▸ ALDH1A1 P00352 4/20 0.52
▸ ALOX15 P16050 1/20 0.52
▸ MYC P01106 1/20 0.51
▸ MAPT P10636 7/20 0.50
▸ MEN1 O00255 7/20 0.50
▸ KMT2A Q03164 7/20 0.50
▸ NPSR1 Q6W5P4 3/20 0.50
▸ GAA P10253 2/20 0.50
▸ PSMD14 O00487 1/20 0.50
▸ HSP90AA1 P07900 1/20 0.50
▸ MMP2 P08253 1/20 0.50
▸ THRB P10828 1/20 0.50
▸ MAPK1 P28482 1/20 0.50
▸ TDP1 Q9NUW8 1/20 0.50
▸ CYP2C19 P33261 1/20 0.49
▸ POLB P06746 3/20 0.47
▸ CCNE2 O96020 1/20 0.47
▸ CCNE1 P24864 1/20 0.47
▸ CDK2 P24941 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1196117 1.00 IDE (0.58) IDEALDH1A1ALOX15MYCMAPT
SCHEMBL68503 0.87 IDE (0.71) IDEALDH1A1ALOX15MYCMAPT
SCHEMBL68504 0.87 IDE (0.71) IDEALDH1A1ALOX15MYCMAPT
SCHEMBL522970 0.81 IDE (0.59) IDEALDH1A1ALOX15MYCMAPT
SCHEMBL31189839 0.81 IDE (0.59) IDEALDH1A1ALOX15MYCMAPT
SCHEMBL522969 0.81 IDE (0.59) IDEALDH1A1ALOX15MYCMAPT
SCHEMBL2481541 0.79 IDE (0.79) IDEALDH1A1ALOX15MYCMAPT
SCHEMBL18768620 0.79 IDE (0.58) IDEALDH1A1ALOX15MYCMAPT
SCHEMBL169230 0.79 IDE (0.79) IDEALDH1A1ALOX15MYCMAPT
Phenol SCHEMBL7057355 0.79 IDE (0.79) IDEALDH1A1ALOX15MYCMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1877434-A2 MODIFIED INTERFERON-GAMMA POLYPEPTIDES AND METHODS FOR USING MODIFIED INTERFERON-GAMMA POLYPEPTIDES Nautilus Biotech (FR) 2008-01-16 — — EP claimed
CN-101094865-A Modified growth hormones NAUTILUS BIOTECH (FR) 2007-12-26 — — CN claimed
EP-1807449-A2 MODIFIED GROWTH HORMONES Nautilus Biotech (FR) 2007-07-18 — — EP claimed
WO-2006120580-A2 MODIFIED INTERFERON-GAMMA POLYPEPTIDES AND METHODS FOR USING MODIFIED INTERFERON-GAMMA POLYPEPTIDES NAUTILUS BIOTECH (FR) 2006-11-16 — — WO claimed
US-20060251619-A1 Modified interferon-gamma polypeptides and methods for using modified interferon-gamma polypeptides HANALL PHARMACEUTICAL CO., LTD. (KR) 2006-11-09 — — US claimed
WO-2006048777-A2 MODIFIED GROWTH HORMONES NAUTILUS BIOTECH (US) 2006-05-11 — — WO claimed
WO-2023250371-A1 ANTIBODY BASED TREATMENT TO REDUCE GUT BACTERIAL GLYCAN AND ASSOCIATED BACTERIA NEW YORK UNIVERSITY (US) 2023-12-28 — — WO disclosed
US-20220184196-A1 METHODS AND COMPOSITIONS FOR TREATING AND DIAGNOSING AUTOIMMUNE DISEASES NEW YORK UNIVERSITY (US) 2022-06-16 — — US disclosed
US-11241488-B2 Methods and compositions for treating and diagnosing autoimmune diseases NEW YORK UNIVERSITY (US) 2022-02-08 — — US disclosed
US-20200061176-A1 METHODS AND COMPOSITIONS FOR TREATING AND DIAGNOSING AUTOIMMUNE DISEASES NEW YORK UNIVERSITY (US) 2020-02-27 — — US disclosed
WO-2018209149-A1 METHODS AND COMPOSITIONS FOR TREATING AND DIAGNOSING AUTOIMMUNE DISEASES NEW YORK UNIVERSITY (US) 2018-11-15 — — WO disclosed
US-9475263-B1 Breathable chemical, biological, radiation, and/or nuclear protection fabric or material MATERIALS MODIFICATION, INC. (US) 2016-10-25 — — US disclosed
EP-2476700-A1 Modified growth hormones HanAll Biopharma Co., Ltd. (KR) 2012-07-18 — — EP disclosed
US-20070249532-A9 Modified growth hormones HANALL BIOPHARMA CO., LTD. (KR) 2007-10-25 — — US disclosed
WO-2007110231-A2 MODIFIED INTERFERON-β (IFN-β) POLYPEPTIDES NAUTILUS BIOTECH, S.A. (FR) 2007-10-04 — — WO disclosed
WO-2007092029-A2 CATALYTIC NANOPARTICLES FOR NERVE-AGENT DESTRUCTION MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2007-08-16 — — WO disclosed
WO-2006120580-A2 MODIFIED INTERFERON-GAMMA POLYPEPTIDES AND METHODS FOR USING MODIFIED INTERFERON-GAMMA POLYPEPTIDES NAUTILUS BIOTECH (FR) 2006-11-16 — — WO disclosed
US-20060251619-A1 Modified interferon-gamma polypeptides and methods for using modified interferon-gamma polypeptides HANALL PHARMACEUTICAL CO., LTD. (KR) 2006-11-09 — — US disclosed
US-20060247170-A1 Modified growth hormones GUYON THIERRY 2006-11-02 — — US disclosed
US-20060094655-A1 Modified growth hormones GUYON THIERRY 2006-05-04 — — US disclosed
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