Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDE | P14735 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | MYC | P01106 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 7/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 4/20 | 0.49 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.49 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31189839 | 1.00 | IDE (0.59) | IDEALDH1A1ALOX15MYCMAPT | |
| SCHEMBL522970 | 1.00 | IDE (0.59) | IDEALDH1A1ALOX15MYCMAPT | |
| SCHEMBL68503 | 0.89 | IDE (0.71) | IDEALDH1A1ALOX15MYCMAPT | |
| SCHEMBL68504 | 0.89 | IDE (0.71) | IDEALDH1A1ALOX15MYCMAPT | |
| SCHEMBL3860617 | 0.84 | CYP3A4 (0.47) | IDEALDH1A1ALOX15MYCMAPT | |
| SCHEMBL3056257 | 0.82 | ALDH1A1 (0.59) | IDEALDH1A1ALOX15MYCMAPT | |
| SCHEMBL18768620 | 0.81 | IDE (0.58) | IDEALDH1A1ALOX15MYCMAPT | |
| SCHEMBL2481541 | 0.81 | IDE (0.79) | IDEALDH1A1ALOX15MYCMAPT | |
| SCHEMBL1196118 | 0.81 | IDE (0.58) | IDEALDH1A1ALOX15MYCMAPT | |
| SCHEMBL169230 | 0.81 | IDE (0.79) | IDEALDH1A1ALOX15MYCMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE44681-E1 | Compositions and methods for inhibiting growth of SMAD4-deficient cancers | BIOGEN IDEC MA INC. (US) | 2013-12-31 | — | — | US | claimed |
| US-20110293512-A1 | Compositions and Methods for Inhibiting Growth of SMAD-4 Deficient Cancers | BIOGEN IDEC MA INC. (US) | 2011-12-01 | — | — | US | claimed |
| US-7927590-B2 | Compositions and methods for inhibiting growth of smad4-deficient cancers | BIOGEN IDEC MA INC. (US) | 2011-04-19 | — | — | US | claimed |
| US-4618565-A | Absorptive layer for optical lithography | RCA CORPORATION (US) | 1986-10-21 | — | — | US | claimed |
| JP-2296245-A | — | — | None | — | — | JP | disclosed |
| CN-106459917-B | Methods of isolating, culturing and genetically engineering immune cell populations for adoptive therapy | 朱诺治疗学股份有限公司 | 2021-03-09 | — | — | CN | disclosed |
| US-20120027754-A1 | Treatment and Prevention of Chronic Asthma Using Antagonists of Integrin AlphavBeta6 | BIOGEN IDEC MA INC. (US) | 2012-02-02 | — | — | US | disclosed |
| US-20110287007-A1 | Treatment and Prevention of Chronic Asthma Using Antagonists of Integrin AlphavBeta6 | BIOGEN IDEC MA INC. (US) | 2011-11-24 | — | — | US | disclosed |
| EP-2087008-A1 | TREATMENT AND PREVENTION OF CHRONIC ASTHMA USING ANTAGONISTS OF INTEGRIN alphaVbeta6 | The Regents of the University of California (US) | 2009-08-12 | — | — | EP | disclosed |
| WO-2008147434-A9 | TREATMENT AND PREVENTION OF CHRONIC ASTHMA USING ANTAGONISTS OF INTEGRIN αVβ6 | UNIV CALIFORNIA (US) | 2009-03-05 | — | — | WO | disclosed |
| US-20090028853-A1 | TREATMENT AND PREVENTION OF CHRONIC ASTHMA USING ANTAGONISTS OF INTEGRIN ALPHAvBETA6 | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, A CALIFORNIA CORPORATION (US) | 2009-01-29 | — | — | US | disclosed |
| WO-2008147434-A1 | TREATMENT AND PREVENTION OF CHRONIC ASTHMA USING ANTAGONISTS OF INTEGRIN αVβ6 | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-12-04 | — | — | WO | disclosed |
| US-5384069-A | Alignment stability, fine and high speed display | CANON KABUSHIKI KAISHA (JP) | 1995-01-24 | — | — | US | disclosed |
| EP-0292244-B1 | POLYMERIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DEVICE | CANON KABUSHIKI KAISHA (JP) | 1993-08-11 | — | — | EP | disclosed |
| US-5066107-A | LIQUID CRYSTAL DISPLAY MEDIUM, LIQUID CRYSTAL DISPLAY METHOD AND LIQUID CRYSTAL DISPLAY APPARATUS FOR OUTPUTTING COLOR IMAGES | CANON KABUSHIKI KAISHA (JP) | 1991-11-19 | — | — | US | disclosed |
| US-5011623-A | Nonlinear optical material and nonlinear optical device | CANON KABUSHIKI KAISHA (JP) | 1991-04-30 | — | — | US | disclosed |
| JP-H02296245-A | PHOTOSENSITIVE COMPOSITION | OKI ELECTRIC IND CO LTD | 1990-12-06 | — | — | JP | disclosed |
| EP-0292244-A2 | Polymeric liquid crystal composition and liquid crystal device | CANON KABUSHIKI KAISHA (JP) | 1988-11-23 | — | — | EP | disclosed |
| US-4618565-A | Absorptive layer for optical lithography | RCA CORPORATION (US) | 1986-10-21 | — | — | US | disclosed |
| US-4618565-A | Absorptive layer for optical lithography | RCA CORPORATION (US) | 1986-10-21 | — | — | US | disclosed |