Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.49 |
| ▸ | DAO | P14920 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 2/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 11/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 11/20 | 0.40 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8251673 | 0.83 | TRPV4 (0.52) | TRPV4DAOMAOAMAOBCYP11B1 | |
| SCHEMBL13548285 | 0.81 | TRPV4 (0.53) | TRPV4DAOMAOAMAOBKCNJ1 | |
| SCHEMBL15046515 | 0.79 | DAO (0.42) | TRPV4DAOMAOAMAOBKCNJ1 | |
| SCHEMBL6564705 | 0.79 | TRPV4 (0.55) | TRPV4DAOMAOAMAOBKCNJ1 | |
| SCHEMBL12436729 | 0.78 | ALDH1A1 (0.45) | DAOMAOAMAOB | |
| SCHEMBL11963202 | 0.78 | TRPV4 (0.50) | TRPV4DAOKCNJ1KCNH2AR | |
| SCHEMBL5316849 | 0.77 | TRPV4 (0.53) | TRPV4DAOMAOAMAOBKCNJ1 | |
| SCHEMBL287322 | 0.77 | TRPV4 (0.53) | TRPV4DAOMAOAMAOBKCNJ1 | |
| Hydrochloric Acid SCHEMBL28803020 | 0.77 | TRPV4 (0.53) | TRPV4DAOMAOAMAOBKCNJ1 | |
| SCHEMBL2389038 | 0.77 | TRPV4 (0.57) | TRPV4DAOMAOAMAOBCYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2489663-A1 | Compounds as syk kinase inhibitors | Almirall, S.A. (ES) | 2012-08-22 | — | — | EP | disclosed |