Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 20/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1197428 | 0.87 | CALCRL (0.47) | CALCRL | |
| SCHEMBL1198426 | 0.86 | CALCRL (0.48) | CALCRL | |
| SCHEMBL1198359 | 0.86 | CALCRL (0.41) | CALCRL | |
| SCHEMBL1197770 | 0.86 | CALCRL (0.56) | CALCRL | |
| SCHEMBL1197771 | 0.81 | CALCRL (0.51) | CALCRL | |
| SCHEMBL2896670 | 0.80 | CALCRL (0.60) | CALCRL | |
| SCHEMBL3705520 | 0.79 | CALCRL (0.52) | CALCRL | |
| SCHEMBL3697359 | 0.79 | CALCRL (0.52) | CALCRL | |
| SCHEMBL13929803 | 0.79 | CALCRL (0.53) | CALCRL | |
| SCHEMBL1198467 | 0.78 | CALCRL (0.49) | CALCRL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7893052-B2 | CGRP receptor antagonists | MERCK SHARP & DOHME LLC | 2011-02-22 | — | — | US | disclosed |