Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 20/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13929804 | 0.88 | CALCRL (0.51) | CALCRL | |
| SCHEMBL13951756 | 0.87 | CALCRL (0.53) | CALCRL | |
| SCHEMBL13929806 | 0.86 | CALCRL (0.53) | CALCRL | |
| SCHEMBL2896670 | 0.85 | CALCRL (0.60) | CALCRL | |
| SCHEMBL13929805 | 0.85 | CALCRL (0.55) | CALCRL | |
| SCHEMBL1198467 | 0.83 | CALCRL (0.49) | CALCRL | |
| SCHEMBL1196576 | 0.79 | CALCRL (0.47) | CALCRL | |
| SCHEMBL14363438 | 0.76 | CALCRL (0.57) | CALCRL | |
| SCHEMBL13951757 | 0.74 | CALCRL (0.54) | CALCRL | |
| SCHEMBL13951567 | 0.74 | CALCRL (0.51) | CALCRL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7491713-B2 | CGRP receptor antagonists | MERCK + CO., INC. (US) | 2009-02-17 | — | — | US | disclosed |
| US-20070287696-A1 | Cgrp Receptor Antagonists | MERCK SHARP & DOHME LLC | 2007-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070287696-A1 | Cgrp Receptor Antagonists | BDKRB1, BDKRB2, CCKBR | CALCRL 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.