SCHEMBL11966276

SCHEMBL11966276

CCC(=O)COCCOCCNC(=O)COCCOCCNC(=O)CC[C@H](NC(=O)CCCCCCCCCCCCCCCCC(=O)O)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.67
▸ NOD1 Q9Y239 5/20 0.47
▸ CCKAR P32238 7/20 0.43
▸ CCKBR P32239 7/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21936997 1.00 GLP1R (0.67) GLP1RNOD1CCKARCCKBR
SCHEMBL25742988 1.00 GLP1R (0.67) GLP1RNOD1CCKARCCKBR
SCHEMBL21936996 1.00 GLP1R (0.67) GLP1RNOD1CCKARCCKBR
SCHEMBL17856855 1.00 GLP1R (0.67) GLP1RNOD1CCKARCCKBR
SCHEMBL13024331 1.00 GLP1R (0.67) GLP1RNOD1CCKARCCKBR
SCHEMBL25851778 1.00 GLP1R (0.67) GLP1RNOD1CCKARCCKBR
SCHEMBL25850145 1.00 GLP1R (0.67) GLP1RNOD1CCKARCCKBR
SCHEMBL12806465 0.98 GLP1R (0.66) GLP1RNOD1CCKARCCKBR
SCHEMBL12806453 0.98 GLP1R (0.66) GLP1RNOD1CCKARCCKBR
SCHEMBL29324606 0.94 GLP1R (0.73) GLP1RNOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230129788-A1 GLP-1/GLP-2 DUAL AGONISTS ZEALAND PHARMA A/S (DK) 2023-04-27 — — US disclosed
US-11111285-B2 Glucagon-GLP-1-GIP triple agonist compounds ZEALAND PHARMA A/S (DK) 2021-09-07 — — US disclosed
US-20190270789-A1 GLUCAGON-GLP-1-GIP TRIPLE AGONIST COMPOUNDS ZEALAND PHARMA A/S (DK) 2019-09-05 — — US disclosed
WO-2016066744-A2 GIP AGONIST COMPOUNDS AND METHODS ZEALAND PHARMA A/S (DK) 2016-05-06 — — WO disclosed
US-20130058999-A1 PHARMACEUTICAL COMPOSITIONS FOR ORAL ADMINISTRATION OF INSULIN PEPTIDES NOVO NORDISK A/S (DK) 2013-03-07 — — US disclosed
US-20120196800-A1 STABLE NON-AQUEOUS LIQUID PHARMACEUTICAL COMPOSITIONS COMPRISING AN INSULIN NOVO NORDISK A/S (DK) 2012-08-02 — — US disclosed
US-20110213131-A1 Method of Acylating a Peptide or Protein NOVO NORDISK A/S (DK) 2011-09-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130058999-A1 PHARMACEUTICAL COMPOSITIONS FOR ORAL ADMINISTRATION OF INSULIN PEPTIDES IAPP, VIP, INSR GLP1R 4/4885NOD1 756/4885CCKAR 144/4885
US-20230129788-A1 GLP-1/GLP-2 DUAL AGONISTS GLP1R, GIPR, GCGR GLP1R 1/4885NOD1 906/4885CCKAR 31/4885
US-11111285-B2 Glucagon-GLP-1-GIP triple agonist compounds GLP1R, GIPR, GCGR GLP1R 1/4885NOD1 1654/4885CCKAR 20/4885
US-20190270789-A1 GLUCAGON-GLP-1-GIP TRIPLE AGONIST COMPOUNDS GLP1R, GIPR, GCGR GLP1R 1/4885NOD1 1654/4885CCKAR 20/4885
US-20120196800-A1 STABLE NON-AQUEOUS LIQUID PHARMACEUTICAL COMPOSITIONS COMPRISING AN INSULIN IAPP, INSR, PNLIP GLP1R 37/4885NOD1 2386/4885CCKAR 799/4885
US-20110213131-A1 Method of Acylating a Peptide or Protein DNPEP, PTMA, ANPEP GLP1R 2584/4885NOD1 4174/4885CCKAR 3127/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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