Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | PPM1B | O75688 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.44 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PPP5C | P53041 | 1/20 | 0.44 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18022167 | 1.00 | KDM4E (0.44) | KDM4EGMNNPPM1BLMNAPPP1CC | |
| SCHEMBL236916 | 1.00 | KDM4E (0.44) | KDM4EGMNNPPM1BLMNAPPP1CC | |
| SCHEMBL236915 | 1.00 | KDM4E (0.44) | KDM4EGMNNPPM1BLMNAPPP1CC | |
| SCHEMBL14544814 | 1.00 | KDM4E (0.44) | KDM4EGMNNPPM1BLMNAPPP1CC | |
| SCHEMBL1109690 | 1.00 | KDM4E (0.44) | KDM4EGMNNPPM1BLMNAPPP1CC | |
| SCHEMBL1105712 | 1.00 | KDM4E (0.44) | KDM4EGMNNPPM1BLMNAPPP1CC | |
| SCHEMBL16408467 | 1.00 | KDM4E (0.44) | KDM4EGMNNPPM1BLMNAPPP1CC | |
| SCHEMBL17732449 | 0.84 | ATM (0.36) | KDM4EGMNNPPM1BLMNAPPP1CC | |
| SCHEMBL12213098 | 0.84 | ATM (0.36) | KDM4EGMNNPPM1BLMNAPPP1CC | |
| SCHEMBL21509276 | 0.73 | KDM4E (0.36) | KDM4EGMNNPPM1BLMNAPPP1CC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170253614-A1 | HEPATITIS C VIRUS INHIBITORS AND USES THEREOF IN PREPARATION OF DRUGS | CHANGZHOU YINSHENG PHARMACEUTICAL CO., LTD. (CN) | 2017-09-07 | — | — | US | disclosed |
| US-8445611-B2 | Antimicrobial polymers | UNIVERSITY OF MASSACHUSETTS (US) | 2013-05-21 | — | — | US | disclosed |
| US-20120195849-A1 | ANTIMICROBIAL POLYMERS | MIDCAP FINANCIAL SBIC, LP, AS ADMINISTRATIVE AGENT | 2012-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170253614-A1 | HEPATITIS C VIRUS INHIBITORS AND USES THEREOF IN PREPARATION OF DRUGS | HAVCR2, HCCS, LIPC | KDM4E 3963/4885GMNN 3067/4885PPM1B 364/4885 |
| US-20120195849-A1 | ANTIMICROBIAL POLYMERS | CGAS, NOD2, NLRP1 | KDM4E 4702/4885GMNN 407/4885PPM1B 3481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.