Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ICMT | O60725 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11976550 | 0.83 | RAB9A (0.43) | KCNH2RAB9ASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL18216916 | 0.81 | RAB9A (0.50) | RAB9ATP53ADORA3TLR8SMN1; SMN2 | |
| SCHEMBL11976545 | 0.80 | RAB9A (0.41) | KCNH2RAB9ATP53SMN1; SMN2KDM4E | |
| SCHEMBL11976551 | 0.76 | HDAC1 (0.39) | KCNH2RAB9ASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL22932773 | 0.76 | SPHK2 (0.46) | KCNH2RAB9ATP53TLR8SMN1; SMN2 | |
| SCHEMBL11976421 | 0.75 | RAB9A (0.46) | RAB9ATP53ADORA3SMN1; SMN2KDM4E | |
| SCHEMBL11976571 | 0.74 | RAB9A (0.48) | RAB9ATP53TLR8CTSSCTSK | |
| SCHEMBL10128326 | 0.73 | TP53 (0.41) | KCNH2TP53ADORA3ADORA2ATLR8 | |
| SCHEMBL14463295 | 0.73 | GCGR (0.46) | KCNH2TLR8SUCNR1ICMTL3MBTL1 | |
| SCHEMBL14576870 | 0.72 | KCNH2 (0.45) | KCNH2RAB9ASMN1; SMN2MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120205585-A1 | METAL COMPLEX, POLYMER COMPOUND AND DEVICE USING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120205585-A1 | METAL COMPLEX, POLYMER COMPOUND AND DEVICE USING THE SAME | HDAC10, EMG1, PRMT1 | KCNH2 379/4885RAB9A 470/4885TP53 4692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.