SCHEMBL10128326

SCHEMBL10128326

CCCCCCCc1ncc(-c2cc(-c3cccc(-c4cccc(C)c4)c3)cc(-c3cccc(-c4cccc(C)c4)c3)c2)cn1

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.41
TLR8 Q9NR97 1/20 0.40
ICMT O60725 10/20 0.39
KCNH2 Q12809 1/20 0.39
GPR84 Q9NQS5 1/20 0.38
CTSS P25774 1/20 0.36
CTSK P43235 1/20 0.36
SIRT2 Q8IXJ6 1/20 0.36
SIRT1 Q96EB6 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
ADORA2A P29274 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13039427 0.95 ICMT (0.39) TP53TLR8ICMTKCNH2SIRT2
SCHEMBL10128361 0.90 KCNH2 (0.38) KCNH2GPR84
SCHEMBL13240269 0.81 RARB (0.51) TP53TLR8ICMTKCNH2CTSS
SCHEMBL10272806 0.78 DHFR (0.44)
SCHEMBL10128421 0.75 RAB9A (0.51) TP53KCNH2
SCHEMBL19185634 0.74 KCNH2 (0.41) TP53KCNH2GPR84ADORA3ADORA2A
SCHEMBL20041788 0.74 KCNH2 (0.41) TP53KCNH2GPR84ADORA3ADORA2A
SCHEMBL19185731 0.74 KCNH2 (0.41) TP53KCNH2GPR84ADORA3ADORA2A
SCHEMBL13681263 0.73 MAP4K4 (0.43)
SCHEMBL11976552 0.73 KCNH2 (0.45) TP53TLR8ICMTKCNH2CTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9082995-B2 Organic EL element and organic EL material-containing solution IDEMITSU KOSAN CO., LTD. (JP) 2015-07-14 US disclosed
US-20130187143-A1 ORGANIC EL DEVICE AND ANTHRACENE DERIVATIVE NISHIMURA KAZUKI (JP) 2013-07-25 US disclosed
US-8436343-B2 Organic EL device IDEMITSU KOSAN CO., LTD. (JP) 2013-05-07 US disclosed
US-8426036-B2 Organic EL device and anthracene derivative IDEMITSU KOSAN CO., LTD. (JP) 2013-04-23 US disclosed
US-8294142-B2 Organic EL device IDEMITSU KOSAN CO., LTD. (JP) 2012-10-23 US disclosed
US-8207526-B2 Organic EL device IDEMITSU KOSAN CO., LTD. (JP) 2012-06-26 US disclosed
US-20110309337-A1 ORGANIC EL DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2011-12-22 US disclosed
US-7829204-B2 Material for organic electroluminescent device and organic electroluminescent device using same IDEMITSU KOSAN CO., LTD. (JP) 2010-11-09 US disclosed
US-20100270539-A1 ORGANIC EL ELEMENT AND ORGANIC EL MATERIAL-CONTAINING SOLUTION IDEMITSU KOSAN CO., LTD. (JP) 2010-10-28 US disclosed
US-20100207110-A1 ORGANIC EL DEVICE IDEMITSU KOSAN CO. LTD (JP) 2010-08-19 US disclosed
US-20100187517-A1 ORGANIC EL DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2010-07-29 US disclosed
US-20100044689-A1 ORGANIC EL DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2010-02-25 US disclosed
US-20070104976-A1 Material for organic electroluminescent device and organic electroluminescent device using same IDEMITSU KOSAN CO., LTD. (JP) 2007-05-10 US disclosed