Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.75 |
| ▸ | USP2 | O75604 | 2/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.75 |
| ▸ | LMNA | P02545 | 1/20 | 0.75 |
| ▸ | MMP9 | P14780 | 1/20 | 0.75 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.75 |
| ▸ | CA1 | P00915 | 16/20 | 0.40 |
| ▸ | CA2 | P00918 | 16/20 | 0.40 |
| ▸ | CA9 | Q16790 | 15/20 | 0.40 |
| ▸ | CA12 | O43570 | 5/20 | 0.39 |
| ▸ | CA7 | P43166 | 5/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.39 |
| ▸ | CA3 | P07451 | 4/20 | 0.39 |
| ▸ | CA4 | P22748 | 4/20 | 0.39 |
| ▸ | CA6 | P23280 | 4/20 | 0.39 |
| ▸ | CA5A | P35218 | 4/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Busulfan SCHEMBL27869023 | 1.00 | TSHR (0.75) | TSHRUSP2KDM4EALDH1A1LMNA | |
| SCHEMBL9689547 | 0.98 | TSHR (0.71) | TSHRUSP2KDM4EALDH1A1LMNA | |
| SCHEMBL5200794 | 0.98 | TSHR (0.71) | TSHRUSP2KDM4EALDH1A1LMNA | |
| SCHEMBL9690280 | 0.98 | TSHR (0.71) | TSHRUSP2KDM4EALDH1A1LMNA | |
| SCHEMBL9690273 | 0.98 | TSHR (0.71) | TSHRUSP2KDM4EALDH1A1LMNA | |
| SCHEMBL9690377 | 0.98 | TSHR (0.71) | TSHRUSP2KDM4EALDH1A1LMNA | |
| SCHEMBL5049329 | 0.92 | — | — | |
| Busulfan SCHEMBL4373 | 0.87 | TSHR (1.00) | TSHRUSP2KDM4EALDH1A1LMNA | |
| Busulfan SCHEMBL4764696 | 0.87 | TSHR (1.00) | TSHRUSP2KDM4EALDH1A1LMNA | |
| SCHEMBL17334965 | 0.84 | TSHR (0.54) | TSHRUSP2KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107970209-A | The improved parenteral formulation of lipophilic pharmaceutical agent and preparation and use its method | 普拉福姆五金器具第二有限公司 | 2018-05-01 | — | — | CN | claimed |
| CN-117940133-A | Therapeutic agents for degradation of mutant BRAF | C4医药公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-117440813-A | EGFR degrading agents for treating brain or CNS cancer metastasis | C4医药公司 | 2024-01-23 | — | — | CN | disclosed |
| CN-115458808-A | Method for producing lithium fluorosulfonate, nonaqueous electrolytic solution, and nonaqueous electrolyte secondary battery | 三菱化学株式会社 | 2022-12-09 | — | — | CN | disclosed |
| CN-111542546-B | anti-LAG-3 antibodies and uses thereof | 四川科伦博泰生物医药股份有限公司 | 2022-08-16 | — | — | CN | disclosed |
| CN-113398070-A | Fractionated radiotherapy and chemotherapy using oxygen therapy | 埃文·C·昂格尔 | 2021-09-17 | — | — | CN | disclosed |
| CN-113387375-A | Method for producing lithium fluorosulfonate, nonaqueous electrolyte solution, and nonaqueous electrolyte secondary battery | 三菱化学株式会社 | 2021-09-14 | — | — | CN | disclosed |
| WO-2021139375-A1 | GLUCOSE-6-PHOSPHATE DEHYDROGENASE MUTANT AND USE THEREOF IN PREPARING DETECTION REAGENT | 北京九强生物技术股份有限公司 | 2021-07-15 | — | — | WO | disclosed |
| CN-108502904-B | Method for producing lithium fluorosulfonate, nonaqueous electrolyte solution, and nonaqueous electrolyte secondary battery | 三菱化学株式会社 | 2021-06-08 | — | — | CN | disclosed |
| CN-111646489-A | Method for producing lithium fluorosulfonate, nonaqueous electrolyte solution, and nonaqueous electrolyte secondary battery | 三菱化学株式会社 | 2020-09-11 | — | — | CN | disclosed |
| US-7750015-B2 | Nitrogen-containing heterocyclic compounds and methods of use thereof | SCHERING CORPORATION (US) | 2010-07-06 | — | — | US | disclosed |
| US-7737155-B2 | Nitrogen-containing heterocyclic compounds and methods of use thereof | SCHERING CORPORATION (US) | 2010-06-15 | — | — | US | disclosed |
| US-7723342-B2 | Heterocycles as nicotinic acid receptor agonists for the treatment of dyslipidemia | SCHERING CORPORATION (US) | 2010-05-25 | — | — | US | disclosed |
| WO-2010000713-A1 | LINEAR-DENDRITIC POLYGLYCEROL COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF | FREIE UNIVERSITÄT BERLIN (DE) | 2010-01-07 | — | — | WO | disclosed |
| WO-2009153668-A2 | METHOD FOR PURIFYING 4-(NITROOXY)BUTYL(2S)-2-(6-METHOXY-2-NAPHTHYL)PROPANOATE | NICOX S.A. (FR) | 2009-12-23 | — | — | WO | disclosed |
| US-20080019978-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF | SCHERING CORPORATION | 2008-01-24 | — | — | US | disclosed |
| CN-1319851-C | Method for producing highly pure solutions using gaseous hydrogen fluoride | HONEYWELL SPECIALTY CHEMICALS (DE) | 2007-06-06 | — | — | CN | disclosed |
| US-20070066630-A1 | Nitrogen-containing heterocyclic compounds and methods of use thereof | MERCK SHARP & DOHME LLC | 2007-03-22 | — | — | US | disclosed |
| CN-1698232-A | Nonaqueous electrolyte solution and lithium secondary battery | MITSUBISHI CHEM CORP (JP) | 2005-11-16 | — | — | CN | disclosed |
| CN-1346331-A | Method for producing high-purity solutions using gaseous hydrogen fluoride | HONEYWELL SPECIALTY CHEMICALS (DE) | 2002-04-24 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080019978-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF | CYP11B2, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CYP11B1 | TSHR 3516/4885USP2 3486/4885KDM4E 2599/4885 |
| US-20070066630-A1 | Nitrogen-containing heterocyclic compounds and methods of use thereof | CYP11B2, CYP11B1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | TSHR 3520/4885USP2 3538/4885KDM4E 2648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.