Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.30 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13292586 | 0.89 | PTGS2 (0.35) | PTGS2CYP19A1CYP11B1CYP11B2ACHE | |
| SCHEMBL11983005 | 0.86 | PTGS2 (0.49) | PTGS2CYP19A1CYP11B1CYP11B2ACHE | |
| SCHEMBL13787109 | 0.85 | PTGS2 (0.30) | PTGS2 | |
| SCHEMBL13292583 | 0.79 | PTGS2 (0.34) | PTGS2CYP19A1CYP11B1CYP11B2ACHE | |
| SCHEMBL11982982 | 0.77 | PTGS2 (0.37) | PTGS2CYP19A1CYP11B1CYP11B2ACHE | |
| SCHEMBL11982990 | 0.76 | CYP1A2 (0.48) | CYP19A1CYP11B1CYP11B2MEN1ALDH1A1 | |
| SCHEMBL13787089 | 0.75 | PTGS2 (0.34) | PTGS2ACHEMEN1ALDH1A1LMNA | |
| SCHEMBL11983041 | 0.75 | KMT2A (0.35) | PTGS2CYP19A1CYP11B1CYP11B2MEN1 | |
| SCHEMBL11983120 | 0.75 | PTGS2 (0.32) | PTGS2 | |
| SCHEMBL13292584 | 0.74 | PTGS2 (0.34) | PTGS2CYP19A1CYP11B1CYP11B2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2075289-B1 | Styryl tetrahydroquinolinium thiol/disulfide compound, process for lightening keratin materials using this dye | OREAL (FR) | 2012-08-15 | — | — | EP | disclosed |