Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11983005 | 0.86 | PTGS2 (0.49) | KMT2AALDH1A1POLBMAPTMEN1 | |
| SCHEMBL14392935 | 0.79 | KMT2A (0.40) | KMT2AKDM4EALDH1A1POLBMAPT | |
| SCHEMBL11982990 | 0.76 | CYP1A2 (0.48) | KMT2AKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL11983040 | 0.75 | PTGS2 (0.35) | KMT2AALDH1A1POLBMAPTMEN1 | |
| SCHEMBL13292586 | 0.75 | PTGS2 (0.35) | CYP19A1CYP11B2CYP11B1PTGS2 | |
| SCHEMBL14392873 | 0.74 | KMT2A (0.35) | KMT2AKDM4EALDH1A1POLBMAPT | |
| SCHEMBL14392881 | 0.73 | KMT2A (0.37) | KMT2AKDM4EALDH1A1POLBMAPT | |
| SCHEMBL11982982 | 0.69 | PTGS2 (0.37) | KMT2AALDH1A1POLBMAPTMEN1 | |
| SCHEMBL18102250 | 0.68 | KDM4A (0.42) | KMT2AKDM4EALDH1A1POLBMAPT | |
| SCHEMBL13840317 | 0.68 | HTT (0.49) | KMT2AKDM4EMAPTBLMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2075289-B1 | Styryl tetrahydroquinolinium thiol/disulfide compound, process for lightening keratin materials using this dye | OREAL (FR) | 2012-08-15 | — | — | EP | disclosed |
| US-7744657-B2 | Styrl tetrahydroquinolinium thiol/disulfide dye compound and method for lightening keratin materials using the same | L'OREAL S.A. (FR) | 2010-06-29 | — | — | US | disclosed |
| EP-2075289-A1 | Styryl tetrahydroquinolinium thiol/disulfide compound, process for lightening keratin materials using this dye | L'Oréal (FR) | 2009-07-01 | — | — | EP | disclosed |
| US-20090126125-A1 | STYRYL TETRAHYDROQUINOLINIUM THIOL/DISULFIDE DYE COMPOUND AND METHOD FOR LIGHTENING KERATIN MATERIALS USING THE SAME | L'OREAL S.A. (FR) | 2009-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090126125-A1 | STYRYL TETRAHYDROQUINOLINIUM THIOL/DISULFIDE DYE COMPOUND AND METHOD FOR LIGHTENING KERATIN MATERIALS USING THE SAME | KRT18, TST, CYBA | KMT2A 1315/4885KDM4E 2113/4885ALDH1A1 542/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.