Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9777887 | 0.79 | ALDH1A1 (0.47) | ALDH1A1HPGDKDM4EMAPTCACNA1B | |
| SCHEMBL21131327 | 0.78 | ALDH1A1 (0.46) | ALDH1A1HPGDKDM4EMAPTCACNA1B | |
| SCHEMBL22791624 | 0.78 | ALDH1A1 (0.46) | ALDH1A1HPGDKDM4EMAPTCACNA1B | |
| SCHEMBL11724822 | 0.77 | ALDH1A1 (0.46) | ALDH1A1HPGDKDM4EMAPTCACNA1B | |
| SCHEMBL16122112 | 0.76 | NPC1 (0.50) | ALDH1A1HPGDKDM4EMAPTCYP3A4 | |
| SCHEMBL12440436 | 0.76 | TP53 (0.48) | ALDH1A1HPGDMAPTCYP3A4TSHR | |
| SCHEMBL11423129 | 0.76 | ALDH1A1 (0.45) | ALDH1A1HPGDKDM4EMAPTCACNA1B | |
| SCHEMBL13724761 | 0.74 | ALDH1A1 (0.44) | ALDH1A1HPGDKDM4EMAPTCACNA1B | |
| SCHEMBL13724762 | 0.74 | ALDH1A1 (0.44) | ALDH1A1HPGDKDM4EMAPTCACNA1B | |
| SCHEMBL14923355 | 0.73 | ALDH1A1 (0.52) | ALDH1A1KDM4EMAPTCYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9068989-B2 | Reagent system and method | LEICA BIOSYSTEMS MELBOURNE PTY LTD (AU) | 2015-06-30 | — | — | US | disclosed |
| US-20120208287-A1 | REAGENT SYSTEM AND METHOD | LEICA BIOSYSTEMS MELBOURNE PTY LTD. (AU) | 2012-08-16 | — | — | US | disclosed |
| WO-2011011826-A1 | REAGENT SYSTEM AND METHOD | LEICA BIOSYSTEMS MELBOURNE PTY LTD (AU) | 2011-02-03 | — | — | WO | disclosed |
| US-7157205-B2 | Intermediate layer composition for multilayer resist process, pattern-forming process using the same, and laminate | FUJI PHOTO FILM CO., LTD. (JP) | 2007-01-02 | — | — | US | disclosed |