SCHEMBL14923355

SCHEMBL14923355

Cc1cc(N)ccc1N=N

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.52
SIGMAR1 Q99720 4/20 0.47
PDE10A Q9Y233 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.45
MAPT P10636 5/20 0.45
CYP3A4 P08684 4/20 0.45
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
KDM4E B2RXH2 3/20 0.45
RAB9A P51151 2/20 0.45
NPC1 O15118 1/20 0.45
CYP1A2 P05177 1/20 0.45
POLB P06746 1/20 0.45
ATM Q13315 1/20 0.45
CASP1 P29466 3/20 0.44
GRIN2D O15399 2/20 0.44
GRIN3B O60391 2/20 0.44
GRIN1 Q05586 2/20 0.44
GRIN2A Q12879 2/20 0.44
GRIN2B Q13224 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13793591 0.85 ALDH1A1 (0.46) ALDH1A1SIGMAR1PDE10AL3MBTL1MAPT
SCHEMBL9611204 0.81 ALDH1A1 (0.61) ALDH1A1SIGMAR1PDE10AL3MBTL1MAPT
SCHEMBL11685094 0.81 ALDH1A1 (0.61) ALDH1A1SIGMAR1PDE10AL3MBTL1MAPT
SCHEMBL24061528 0.78 ALDH1A1 (0.48) ALDH1A1SIGMAR1PDE10AL3MBTL1MAPT
SCHEMBL12588150 0.77 ALDH1A1 (0.52) ALDH1A1SIGMAR1PDE10AL3MBTL1MAPT
SCHEMBL14679678 0.77 ALDH1A1 (0.52) ALDH1A1SIGMAR1PDE10AL3MBTL1MAPT
SCHEMBL13356364 0.76 TDP1 (0.48) ALDH1A1SIGMAR1L3MBTL1MAPTCYP3A4
SCHEMBL16122112 0.76 NPC1 (0.50) ALDH1A1L3MBTL1MAPTCYP3A4MEN1
SCHEMBL18084260 0.76 ALDH1A1 (0.56) ALDH1A1SIGMAR1PDE10AL3MBTL1MAPT
SCHEMBL19526398 0.74 SIGMAR1 (0.57) ALDH1A1SIGMAR1PDE10AL3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3015516-A1 INK COMPOSITION, INK JET RECORDING METHOD USING SAME, AND COLORED MATERIAL Nippon Kayaku Kabushiki Kaisha (JP) 2016-05-04 EP disclosed
EP-2589631-A1 INK COMPOSITION, INKJET RECORDING METHOD AND COLORED BODY Nippon Kayaku Kabushiki Kaisha (JP) 2013-05-08 EP disclosed